| Time-dependent changes of amino acids in the serum, liver, brain and urine of rats administered with theanine. | |
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MedLine Citation:
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PMID: 10361674 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Time-dependent changes of theanine (gamma-glutamylethylamide) and other amino acids in various tissues of rats were investigated during the 24 hrs after theanine administration. When theanine (4 g/kg of body weight) was intragastrically administered to rats, the concentrations of theanine in the serum, liver and brain were significantly increased 1 hr after its administration, and thereafter gradually decreased, but reached the maximum level in the brain after 5 hrs. Theanine in these tissues had completely disappeared 24 hrs after its administration. In contrast, the administration of theanine resulted in the concentrations of theanine, urea, ethylamine and glutamic acid in the urine being significantly enhanced. These results suggest that theanine might be degraded via glutamic acid. |
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Authors:
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T Terashima; J Takido; H Yokogoshi |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Bioscience, biotechnology, and biochemistry Volume: 63 ISSN: 0916-8451 ISO Abbreviation: Biosci. Biotechnol. Biochem. Publication Date: 1999 Apr |
Date Detail:
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Created Date: 1999-07-26 Completed Date: 1999-07-26 Revised Date: 2003-11-14 |
Medline Journal Info:
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Nlm Unique ID: 9205717 Medline TA: Biosci Biotechnol Biochem Country: JAPAN |
Other Details:
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Languages: eng Pagination: 615-8 Citation Subset: IM |
Affiliation:
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School of Food and Nutritional Sciences, University of Shizuoka, Japan. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Amino Acids
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blood,
metabolism*,
urine Animals Brain Chemistry / drug effects* Glutamates / pharmacology* Liver / drug effects, metabolism* Male Rats Rats, Wistar Time Factors |
| Chemical | |
Reg. No./Substance:
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0/Amino Acids; 0/Glutamates; 3081-61-6/theanine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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