| Time-dependency of sensory evoked potentials in comatose cardiac arrest survivors. | |
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MedLine Citation:
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PMID: 11511943 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: To assess the validity of early sensory evoked potential (SEP) recording for reliable outcome prediction in comatose cardiac arrest survivors within 48 h after restoration of spontaneous circulation (ROSC). DESIGN AND SETTING: Prospective cohort study in a medical intensive care unit of a university hospital. PATIENTS: Twenty-five comatose, mechanically ventilated patients following cardiopulmonary resuscitation MEASUREMENTS AND RESULTS: Median nerve short- and long-latency SEP were recorded 4, 12, 24, and 48 h after ROSC. Cortical N20 peak latency and cervicomedullary conduction time decreased (improved) significantly between 4, 12, and 24 h after resuscitation in 22 of the enrolled patients. There was no further change in short-latency SEP at 48 h. The cortical N70 peak was initially detectable in seven patients. The number of patients with increased N70 peak increased to 11 at 12 h and 14 at 24 h; there was no further change at 48 h. Specificity of the N70 peak latency (critical cutoff 130 ms) increased from 0.43 at 4 h to 1.0 at 24 h after ROSC. Sensitivity decreased from 1.0 at 4 h to 0.83 at 24 h after ROSC. CONCLUSION: Within 24 h after ROSC there was a significant improvement in SEP. Therefore we recommend allowing a period of at least 24 h after cardiopulmonary resuscitation for obtaining a reliable prognosis based on SEP. |
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Authors:
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A Gendo; L Kramer; M Häfner; G C Funk; C Zauner; F Sterz; M Holzer; E Bauer; C Madl |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Intensive care medicine Volume: 27 ISSN: 0342-4642 ISO Abbreviation: Intensive Care Med Publication Date: 2001 Aug |
Date Detail:
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Created Date: 2001-08-20 Completed Date: 2001-11-01 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 7704851 Medline TA: Intensive Care Med Country: United States |
Other Details:
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Languages: eng Pagination: 1305-11 Citation Subset: IM |
Affiliation:
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Department of Internal Medicine IV, Intensive Care Unit 13 H1, University of Vienna, Währinger Gürtel 18-20, 1090 Vienna, Austria. alexandra.gendo@univie.ac.at |
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Aged, 80 and over Analysis of Variance Austria / epidemiology Cardiopulmonary Resuscitation Coma / diagnosis*, etiology, mortality Evoked Potentials, Somatosensory* Female Heart Arrest / complications*, mortality Humans Male Middle Aged Predictive Value of Tests Prognosis Prospective Studies Sensitivity and Specificity Time Factors |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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