| Time course and interrelation of reperfusion-induced ST changes and ventricular arrhythmias in acute myocardial infarction. | |
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MedLine Citation:
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PMID: 1951071 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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With the increasing use of thrombolytic therapy, the presence and time course of reperfusion-induced ventricular arrhythmias and ST-segment changes have become of particular interest. Technical improvements in bipolar Holter monitoring offer the opportunity to record both parameters continuously and simultaneously. Time course and interaction of both parameters in dependence on the onset of thrombolysis and time of reperfusion were investigated in 30 patients with acute myocardial infarction. Reperfusion was achieved in 20 patients after 49 +/- 23 minutes and in another 2 patients after 120 minutes (73%, group A). Vascular occlusion persisted in 8 patients for greater than 24 hours (group B). Sudden ST-segment changes (greater than 0.2 mV/15 min) in the bipolar leads indicated reperfusion in 7 of 22 patients (32%). Idioventricular rhythms, most frequent in reperfused patients (group A: 18 of 22 patients, mean 121 beats/hour), were unspecific reperfusion markers (group B: 5 of 8 patients, 1 beat/hour) unless frequent (p less than 0.05) or longer lasting, repetitive (p less than 0.01) episodes were considered. Premature ventricular beats and couplets (p less than 0.05) were also most frequent in group A (peak frequency 3 to 5 hours after thrombolysis). Ventricular tachycardia observed in 21 of 22 patients (95%) in group A and in 3 of 8 (38%) in group B (p less than 0.01) attained their peak frequency 7 to 9 hours after thrombolysis. They occurred most often in anterior myocardial infarction and were often preceded by frequent singular premature beats (r = 0.78).(ABSTRACT TRUNCATED AT 250 WORDS) |
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Authors:
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M Zehender; S Utzolino; A Furtwängler; W Kasper; T Meinertz; H Just |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The American journal of cardiology Volume: 68 ISSN: 0002-9149 ISO Abbreviation: Am. J. Cardiol. Publication Date: 1991 Nov |
Date Detail:
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Created Date: 1991-11-27 Completed Date: 1991-11-27 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0207277 Medline TA: Am J Cardiol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 1138-42 Citation Subset: AIM; IM |
Affiliation:
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Innere Medizin III, Albert-Ludwigs Universität Freiburg, Federal Republic of Germany. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Arrhythmias, Cardiac / etiology, physiopathology* Electrocardiography* Female Humans Male Middle Aged Myocardial Infarction / complications, physiopathology*, therapy Myocardial Reperfusion* Thrombolytic Therapy |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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