| Time course for entry of intestinally infused lipids into blood of rats. | |
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MedLine Citation:
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PMID: 7653667 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The early time course of the absorption of duodenally infused 14C-labeled Intralipid into either the hepatic portal circulation or systemic circulation was measured. Plasma radioactivity did not increase significantly at either site until 30 min after the intestinal infusion began and was maximal between 60 and 120 min. In studies on the effects of intestinal lipid infusions on sham feeding in rats we find significant suppressions of sham feeding after only 10 min. Thus the time course for lipid absorption is different from that of the satiating effects of duodenally infused fats. These results are consistent with the hypothesis that the satiating effect of fats infused into the small intestine occurs before entry of absorbed fats into the blood and is not dependent on recently absorbed circulating fat. |
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Authors:
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D Greenberg; R A Kava; D R Lewis; M R Greenwood; G P Smith |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: The American journal of physiology Volume: 269 ISSN: 0002-9513 ISO Abbreviation: Am. J. Physiol. Publication Date: 1995 Aug |
Date Detail:
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Created Date: 1995-09-22 Completed Date: 1995-09-22 Revised Date: 2007-11-14 |
Medline Journal Info:
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Nlm Unique ID: 0370511 Medline TA: Am J Physiol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: R432-6 Citation Subset: IM |
Affiliation:
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Department of Psychiatry, Cornell University Medical College, New York Hospital-Cornell Medical Center, Westchester Division, White Plains 10605, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Catheterization Duodenum Fat Emulsions, Intravenous / metabolism Intestinal Absorption Intestines / metabolism* Lipid Metabolism* Lipids / blood Male Rats Rats, Sprague-Dawley Time Factors |
| Grant Support | |
ID/Acronym/Agency:
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DK-26687/DK/NIDDK NIH HHS; DK-38757/DK/NIDDK NIH HHS; MH-40010/MH/NIMH NIH HHS |
| Chemical | |
Reg. No./Substance:
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0/Fat Emulsions, Intravenous; 0/Lipids |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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