Document Detail

Time course of the effects of orthokeratology on peripheral refraction and corneal topography.
MedLine Citation:
PMID:  23347397     Owner:  NLM     Status:  Publisher    
PURPOSE: To describe the time course of changes in both peripheral refraction and corneal topography in myopic adults wearing myopic orthokeratology (OK) lenses. METHODS: Nineteen adult myopes were fitted with OK lenses in both eyes for overnight wear. Central and peripheral refraction and corneal topography were measured along the horizontal meridian at baseline and after 1, 4, 7 and 14 nights of lens wear. RESULTS: At baseline, refraction was myopic at all positions along the horizontal meridian. Two weeks of OK lens wear caused a significant change in refraction where the general trend was a hyperopic shift in spherical equivalent (M) except at 35° in the nasal visual field where there was instead a myopic shift in M. The most significant change in M occurred between baseline and after 1 night of OK lens wear and the effect became less dramatic across subsequent days of OK treatment. Similarly, OK caused significant change in corneal refractive power at all positions along the horizontal corneal chord. There was a reduction in corneal power or flattening of the cornea at all positions except at 2.4 mm and 2.8 mm on the nasal cornea where there was an increase in corneal refractive power or steepening of the cornea. This change was most apparent after 1 night of OK lens wear and, similar to changes in peripheral refraction, changes in corneal refractive power on subsequent days of OK treatment became less marked. CONCLUSIONS: Orthokeratology caused significant changes in both peripheral refraction and corneal topography. The greatest change in refraction and corneal refractive power across the horizontal corneal meridian occurred during the first night of OK lens wear. Subsequent changes in both peripheral refraction and corneal topography were less dramatic, in the same manner as reported changes in apical radius and central refraction after OK. This study confirms that with OK treatment, the peripheral retina experiences myopic defocus, which is conjectured to underlie the observed slowing of myopia progression.
Pauline Kang; Helen Swarbrick
Related Documents :
24255047 - Longitudinal detection of optic nerve head changes by spectral domain optical coherence...
25118827 - Evaluation of visual acuity, macular status, and subfoveal choroidal thickness changes ...
15559807 - Experimental study on pollutant movement in surf zone.
58767 - Evidence for the presence of eye movement potentials during paradoxical sleep in cats.
15802257 - Comparing night-to-night variability of sleep measures in elderly african americans and...
16364297 - Upregulation of rage and its ligands in proliferative retinal disease.
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-1-24
Journal Detail:
Title:  Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists)     Volume:  -     ISSN:  1475-1313     ISO Abbreviation:  Ophthalmic Physiol Opt     Publication Date:  2013 Jan 
Date Detail:
Created Date:  2013-1-25     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8208839     Medline TA:  Ophthalmic Physiol Opt     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Ophthalmic & Physiological Optics © 2013 The College of Optometrists.
School of Optometry and Vision Science, The University of New South Wales, Sydney, Australia.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Adsorption and Dilational Rheology of Mixed ß-Casein/DoTAB Layers Formed by Sequential and Simultan...
Next Document:  Innate immune markers that distinguish red deer (Cervus elaphus) selected for resistant or susceptib...