Document Detail

Time course of accommodation after implantable collamer lens implantation.
MedLine Citation:
PMID:  18692166     Owner:  NLM     Status:  MEDLINE    
PURPOSE: To assess the time course of accommodative function after Implantable Collamer Lens (ICL) implantation and to investigate the relationship between patient age and accommodation in ICL-implanted eyes. DESIGN: Prospective, nonrandomized clinical trial. METHODS: We prospectively examined 69 eyes of 40 consecutive patients with myopic refractive errors of -3.25 to -22.75 diopters (D) who were undergoing ICL implantation. We assessed the amplitude of accommodation using an accommodometer before and one, three, six, and 12 months after surgery. We also investigated its relationship with patient age. RESULTS: The accommodation was 6.36 +/- 3.94 D (mean +/- standard deviation) before surgery and 4.89 +/- 2.72 D, 4.98 +/- 2.67 D, 5.16 +/- 2.72 D, and 5.72 +/- 2.85 D at one, three, six, and 12 months after surgery, respectively. The variance of data was statistically significant (P = .02, repeated-measures analysis of variance). Multiple comparisons demonstrated significant differences between measurements made before surgery and at one month after (P = .004, Fisher least significant difference test), before surgery and at three months after (P = .007), and before surgery and at six months after (P = .01). There was a significant correlation between patient age and accommodation before (Pearson correlation coefficient, r = -0.665; P < .001) and one year after (r = -0.803; P < .001) ICL implantation. CONCLUSIONS: Accommodation was impaired transiently in the early postoperative periods, and then recovered gradually over time, indicating that transient dysfunction of the ciliary muscles by ICL fixation may occur after ICL implantation even if the crystalline lens remained intact. As patients aged, the amplitude of accommodation became significantly smaller not only in normal eyes but also in ICL-implanted eyes.
Kazutaka Kamiya; Kimiya Shimizu; Daisuke Aizawa; Hitoshi Ishikawa
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Publication Detail:
Type:  Clinical Trial; Journal Article     Date:  2008-08-09
Journal Detail:
Title:  American journal of ophthalmology     Volume:  146     ISSN:  1879-1891     ISO Abbreviation:  Am. J. Ophthalmol.     Publication Date:  2008 Nov 
Date Detail:
Created Date:  2008-11-05     Completed Date:  2008-12-02     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0370500     Medline TA:  Am J Ophthalmol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  674-8     Citation Subset:  AIM; IM    
Department of Ophthalmology, University of Kitasato School of Medicine, Kanagawa, Japan.
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MeSH Terms
Accommodation, Ocular*
Age Factors
Cataract / complications,  etiology,  physiopathology
Lens Implantation, Intraocular*
Longitudinal Studies
Middle Aged
Myopia / complications,  surgery
Phakic Intraocular Lenses
Postoperative Complications
Postoperative Period
Time Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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