Document Detail

Time trend and geographic distribution of treated patients with congenital hypothyroidism relative to the number of available endocrinologists in Japan.
MedLine Citation:
PMID:  20227725     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To investigate the time trend and geographic distribution of treated patients with congenital hypothyroidism (CH) and explore their possible relationship to the availability of endocrinologists in Japan. STUDY DESIGN: The 2-source capture-recapture method was used to estimate the total number of patients. The ratio of the total estimated number of patients with CH to the number of endocrinologists and Spearman correlation coefficients were calculated. Curve fitting for changes in incidence or prevalence was estimated. RESULTS: The incidence and prevalence of CH exhibited upward trends, with linear slopes of increase during the period 1994-2002. A statistically significant positive correlation was observed between the prevalence of CH and the ratio of the number of patients with CH to the number of endocrinologists in the 10 regions studied. The prevalence of CH was significantly higher in the regions with a higher ratio of patients with CH to endocrinologists, and also in younger patients. CONCLUSIONS: A shortage of endocrinologists may be one reason for the upward trend in the incidence and prevalence of treated patients with CH.
Yan-Hong Gu; Tadaaki Kato; Shohei Harada; Hiroaki Inomata; Kikumaro Aoki
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2010-03-15
Journal Detail:
Title:  The Journal of pediatrics     Volume:  157     ISSN:  1097-6833     ISO Abbreviation:  J. Pediatr.     Publication Date:  2010 Jul 
Date Detail:
Created Date:  2010-06-15     Completed Date:  2010-09-03     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0375410     Medline TA:  J Pediatr     Country:  United States    
Other Details:
Languages:  eng     Pagination:  153-7     Citation Subset:  AIM; IM    
Copyright Information:
Copyright (c) 2010 Mosby, Inc. All rights reserved.
Department of Health Policy, National Research Institute for Child Health and Development, Tokyo, Japan.
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MeSH Terms
Congenital Hypothyroidism / drug therapy*,  epidemiology*
Follow-Up Studies
Health Services Accessibility / statistics & numerical data*,  trends
Infant, Newborn
Japan / epidemiology
Neonatal Screening / methods
Physicians / statistics & numerical data*
Retrospective Studies
Risk Factors
Specialization / statistics & numerical data*
Statistics, Nonparametric
Time Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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