Document Detail


Tilt test results in young and elderly patients with syncope of unknown origin.
MedLine Citation:
PMID:  9061128     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The effects of aging on the results of prolonged drug-free tilt testing were studied in 175 consecutive patients with unexplained syncope divided into 3 groups: 59 patients < 40 years old; 57 patients between 40 and 60 years; and 59 patients > 60 years old. Tilt-induced vaso-vagal syncope occurred respectively in 17 (29%), 20 (35%), and 18 patients (31%) in the 3 age groups. Vasodepressor, mixed, and cardioinhibitory vaso-vagal syncope occurred similarly in the 3 groups; organic heart disease and systemic hypertension were more frequent in elderly patients without affecting the incidence of tilt-induced syncope. Blood pressure and heart rate variations during syncope were similar in the 3 age groups; in the first 20 minutes of tilt testing, before the appearance of the vaso-vagal reflex, elderly patients showed greater reduction in blood pressure and smaller increase in heart rate than younger patients. Our data indicate that increasing age determines a different blood pressure and heart rate behavior during tilt testing, but apparently does not influence the incidence of vaso-vagal syncope in patients with syncope of undetermined etiology. As the proportion of patients with a positive isoproterenol tilt test was reported to decline with age, our results suggest that the reduced incidence of syncope during isoproterenol tilt testing could be the expression of impaired autonomic response among elderly syncope patients.
Authors:
E Marangoni; A Zucchi; F Lissoni; A Oddone; P Ferraris; G Galloni; M C Zappa; M Orlandi
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Aging (Milan, Italy)     Volume:  8     ISSN:  0394-9532     ISO Abbreviation:  Aging (Milano)     Publication Date:  1996 Dec 
Date Detail:
Created Date:  1997-05-23     Completed Date:  1997-05-23     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9102503     Medline TA:  Aging (Milano)     Country:  ITALY    
Other Details:
Languages:  eng     Pagination:  409-16     Citation Subset:  IM    
Affiliation:
Division of Cardiology, Ospedale Maggiore, Lodi, Italy.
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Aging / physiology*
Blood Pressure
Female
Heart Rate
Humans
Incidence
Male
Middle Aged
Syncope / diagnosis*,  etiology,  physiopathology
Tilt-Table Test*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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