Document Detail

Tick salivary prostaglandins: Presence, origin and significance.
MedLine Citation:
PMID:  15275289     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Prostaglandins (PGs) are oxygenated metabolites of polyunsaturated fatty acids, most notably arachidonic acid, that act as 'local hormones', regulating a plethora of physiological processes in mammals and other vertebrates. For a long time, PGs were reported only in higher vertebrates, but more recently they have been reported in lower organisms such as bacteria, yeasts and protozoa, and much information is now available on PGs in insects. Prostaglandins are increasingly reported to exist at the host-parasite interface and are thought to aid the parasite by modulating the inflammatory and immune response. Ticks secrete saliva containing extremely high concentrations of PGs into the host, and in this article Alan Bowman, Jack Dillwith and John Sauer provide a synopsis of the information, to date, on the presence, synthesis and proposed roles for these tick salivary PGs.
A S Bowman; J W Dillwith; J R Sauer
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Parasitology today (Personal ed.)     Volume:  12     ISSN:  0169-4758     ISO Abbreviation:  Parasitol. Today (Regul. Ed.)     Publication Date:  1996 Oct 
Date Detail:
Created Date:  2004-07-27     Completed Date:  2005-04-12     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8605563     Medline TA:  Parasitol Today     Country:  England    
Other Details:
Languages:  eng     Pagination:  388-96     Citation Subset:  -    
Department of Entomology, 127 Noble Research Center, Oklahoma State University, Stillwater, OK 74078-0464, USA.
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