Document Detail


Ticarcillin-clavulanate therapy for infections with ticarcillin-resistant microorganisms.
MedLine Citation:
PMID:  2705069     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
In a prospective study, 46 episodes of serious infection with ticarcillin-resistant microorganisms were treated with the combination ticarcillin disodium and clavulanate potassium (Timentin). Clinical cure was achieved in 35 of the 46 episodes (76%), and microbiologic eradication was achieved in 30 (65%). We found no development of resistance to ticarcillin-clavulanate and observed no serious side effects.
Authors:
M S Gelfand; R D Lawson; W Baucom
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Southern medical journal     Volume:  82     ISSN:  0038-4348     ISO Abbreviation:  South. Med. J.     Publication Date:  1989 Apr 
Date Detail:
Created Date:  1989-05-22     Completed Date:  1989-05-22     Revised Date:  2005-11-17    
Medline Journal Info:
Nlm Unique ID:  0404522     Medline TA:  South Med J     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  433-7     Citation Subset:  AIM; IM    
Affiliation:
Department of Medicine, Methodist Hospitals of Memphis, TN 38104.
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Aged, 80 and over
Bacterial Infections / drug therapy*
Clavulanic Acids / pharmacology,  therapeutic use*
Drug Therapy, Combination / pharmacology,  therapeutic use
Female
Gram-Negative Bacteria / drug effects
Humans
Male
Middle Aged
Penicillin Resistance
Penicillins / therapeutic use*
Prospective Studies
Ticarcillin / pharmacology,  therapeutic use*
Chemical
Reg. No./Substance:
0/Clavulanic Acids; 0/Penicillins; 34787-01-4/Ticarcillin; 86482-18-0/ticarcillin-clavulanic acid

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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