Document Detail

Tibial dyschondroplasia in single-comb White Leghorn chicks fed tetramethylthiuram disulfide (a fungicide).
MedLine Citation:
PMID:  3833229     Owner:  NLM     Status:  MEDLINE    
Supplementing a practical chick starter diet with 30 mg tetramethylthiuram disulfide per kg of diet produced tibial dyschondroplasia (TD) in single-comb white leghorn chicks without compromising growth or bone mineralization. The incidence and severity of the lesion increased over time, with the highest incidence (40%) occurring in 4-week-old chickens. Microscopically, the lesion was consistent with the description of TD in broilers. This is the first known report of TD in the layer-type chick, which heretofore was felt to be highly resistant to TD.
J R Veltmann; G N Rowland; S S Linton
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Avian diseases     Volume:  29     ISSN:  0005-2086     ISO Abbreviation:  Avian Dis.     Publication Date:    1985 Oct-Dec
Date Detail:
Created Date:  1986-05-01     Completed Date:  1986-05-01     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  0370617     Medline TA:  Avian Dis     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1269-72     Citation Subset:  IM    
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MeSH Terms
Osteochondrodysplasias / chemically induced,  veterinary*
Poultry Diseases / chemically induced*
Thiocarbamates / adverse effects*
Thiram / adverse effects*
Tibia / drug effects,  pathology
Time Factors
Reg. No./Substance:
0/Thiocarbamates; 137-26-8/Thiram

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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