| Tiagabine. | |
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MedLine Citation:
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PMID: 8039477 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Tiagabine (TGB), a specific gamma-aminobutyric acid (GABA)-uptake inhibitor, is a potential new antiepileptic drug with a novel mechanism of action. In animal models of epilepsy as well as in a placebo-controlled trial in patients with complex partial seizures, TGB showed significant anticonvulsant effects. TGB was well tolerated by most patients. |
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Authors:
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H Mengel |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Epilepsia Volume: 35 Suppl 5 ISSN: 0013-9580 ISO Abbreviation: Epilepsia Publication Date: 1994 |
Date Detail:
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Created Date: 1994-08-25 Completed Date: 1994-08-25 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 2983306R Medline TA: Epilepsia Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: S81-4 Citation Subset: IM |
Affiliation:
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Novo Nordisk A/S, Måløv, Denmark. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Acoustic Stimulation Animals Anticonvulsants / pharmacokinetics, pharmacology*, therapeutic use Clinical Trials as Topic Drug Evaluation, Preclinical Drug Interactions Epilepsy, Complex Partial / drug therapy Humans Male Mice Nipecotic Acids / pharmacokinetics, pharmacology*, therapeutic use Rats Rats, Wistar Seizures / prevention & control |
| Chemical | |
Reg. No./Substance:
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0/Anticonvulsants; 0/Nipecotic Acids; 115103-54-3/tiagabine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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