Document Detail

Thyroxine screening values in premature infants.
MedLine Citation:
PMID:  9642638     Owner:  NLM     Status:  MEDLINE    
OBJECTIVES: Premature infants often have low thyroxine levels when compared to fullterm infants. We sought to determine gestational age specific normal ranges for thyroxine screening results for premature infants in neonatal intensive care units. METHODS: Thyroid screening results for infants less than 38 weeks gestation admitted to two NICUs were examined. For each sample the thyroxine Z-score was computed using parameters from fullterm infants. The mean thyroxine Z-score was calculated for each gestational age for days of life 1, 2, 3-7, 8-14, 15-21, 22-28, and 29-60. RESULTS: There were 1144 specimens obtained from 543 premature infants. The mean thyroxine Z-score was below 0 for almost every gestational age and days-of-life category. The mean thyroxine Z-score increased with gestational age, but did not rise with increasing postpartum age. CONCLUSION: The data show that normal thyroxine Z-scores for premature infants are lower than for fullterm infants and remain low at least as long as the infants remain ill.
J Saslow; E M Post; C A Southard; G M Stuart; M Fernandes D'Souza
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of pediatric endocrinology & metabolism : JPEM     Volume:  11     ISSN:  0334-018X     ISO Abbreviation:  J. Pediatr. Endocrinol. Metab.     Publication Date:    1998 Mar-Apr
Date Detail:
Created Date:  1998-09-01     Completed Date:  1998-09-01     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9508900     Medline TA:  J Pediatr Endocrinol Metab     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  235-9     Citation Subset:  IM    
Department of Pediatrics, Children's Regional Hospital, Cooper Hospital/University Medical Center, Robert Wood Johnson Medical School at Camden, NJ 08103, USA.
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MeSH Terms
Gestational Age
Infant, Newborn
Infant, Premature*
Neonatal Screening
Retrospective Studies
Thyroxine / blood*
Reg. No./Substance:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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