Document Detail


Thyrotropin-releasing hormone precursor gene knocking down impedes melanocortin-induced hypertension in rats.
MedLine Citation:
PMID:  18559717     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Authors:
María S Landa; Silvia I García; Mariano L Schuman; Azucena L Alvarez; Samuel Finkielman; Carlos J Pirola
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Publication Detail:
Type:  Comment; Letter; Research Support, Non-U.S. Gov't     Date:  2008-06-16
Journal Detail:
Title:  Hypertension     Volume:  52     ISSN:  1524-4563     ISO Abbreviation:  Hypertension     Publication Date:  2008 Aug 
Date Detail:
Created Date:  2008-07-24     Completed Date:  2008-08-22     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7906255     Medline TA:  Hypertension     Country:  United States    
Other Details:
Languages:  eng     Pagination:  e8; author reply e9     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Disease Models, Animal
Down-Regulation
Genetic Predisposition to Disease
Hypertension / drug therapy,  genetics*,  metabolism*
Leptin / administration & dosage
Melanocortins / metabolism
Protein Precursors / administration & dosage
Rats
Rats, Inbred SHR
Rats, Wistar
Thyrotropin-Releasing Hormone / administration & dosage,  genetics*,  metabolism*
alpha-MSH / administration & dosage,  analogs & derivatives
Chemical
Reg. No./Substance:
0/Leptin; 0/Melanocortins; 0/Protein Precursors; 0/acetyl-norleucyl(4)-(aspartyl(5)-histidyl(6)-phenylalanyl(7)-arginyl(8)-tryptophyl(9)-lysyl(10))cyclo-alpha-MSH(4-10)amide; 100469-84-9/prepro-thyrotropin-releasing hormone; 24305-27-9/Thyrotropin-Releasing Hormone; 581-05-5/alpha-MSH
Comments/Corrections
Comment On:
Hypertension. 2008 Apr;51(4):884-90   [PMID:  18285617 ]

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