Document Detail

Thyrotoxic period paralysis: report of three cases and review of the literature.
MedLine Citation:
PMID:  10497629     Owner:  NLM     Status:  MEDLINE    
Thyrotoxic periodic paralysis (TPP) is a neuromuscular disorder that, in a global perspective, only affects a small percentage of patients with thyrotoxicosis of any aetiology, but is a fairly common phenomenon in Asian populations where it predominantly occurs in males. Three typical cases are presented here. All three patients were Asian males, one being the first Laotian patient reported to have this disorder. In one case prodromal symptoms of TPP occurred during a relapse of the thyrotoxicosis. The epidemiology, clinical manifestations, aetiology and treatment of this relatively rare condition are discussed. As oriental races are now frequently encountered in the Western world, it is imperative that TPP is included in the differential diagnosis of muscle weakness in order to avoid the life-threatening complications of hypokalaemia and thyrotoxicosis.
K I Papadopoulos; T Diep; B Cleland; N W Lunn
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Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  Journal of internal medicine     Volume:  241     ISSN:  0954-6820     ISO Abbreviation:  J. Intern. Med.     Publication Date:  1997 Jun 
Date Detail:
Created Date:  1999-10-13     Completed Date:  1999-10-13     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  8904841     Medline TA:  J Intern Med     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  521-4     Citation Subset:  IM    
Department of Medicine, Fairfield Hospital, New South Wales, Australia.
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MeSH Terms
Diagnosis, Differential
Paralysis / etiology*
Thyroid Hormones / blood*
Thyrotoxicosis / blood,  complications*,  diagnosis*
Reg. No./Substance:
0/Thyroid Hormones

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