Document Detail


Thyroide hormone resistance syndromes.
MedLine Citation:
PMID:  21459689     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Thyroid hormone resistance syndromes are a group of genetic conditions characterized by decreased tissue sensitivity to thyroid hormones. Three syndromes, in which resistance to hormone action is respectively due to mutations in the gene encoding for thyroid hormone receptor TRβ, impaired T4 and T3 transport, and impaired conversion of T4 to T3 mediated by deiodinases. An updated review of each of these forms of resistance is provided, and their pathogenetic mechanisms and clinical approaches are discussed.
Authors:
Juan Bernal
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-4-1
Journal Detail:
Title:  Endocrinologia y nutricion : organo de la Sociedad Espanola de Endocrinologia y Nutricion     Volume:  -     ISSN:  1579-2021     ISO Abbreviation:  -     Publication Date:  2011 Apr 
Date Detail:
Created Date:  2011-4-4     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100886482     Medline TA:  Endocrinol Nutr     Country:  -    
Other Details:
Languages:  ENG; SPA     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2010 SEEN. Published by Elsevier Espana. All rights reserved.
Affiliation:
Instituto de Investigaciones Biomédicas, CSIC-UAM y CIBER de enfermedades raras, Madrid, España.
Vernacular Title:
Síndromes de resistencia a las hormonas tiroideas.
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