| Thyroid volumetric quantification: comparative evaluation between conventional and volumetric ultrasonography. | |
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MedLine Citation:
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PMID: 19022998 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: Thyroid volume quantification is an important parameter for radiotherapy dosing in cases of major thyroid diseases such as thyroiditis and carcinoma. In clinical practice, this calculation is performed by means of ultrasonography on the basis of an ellipsoid formula obtained from the 3 axes. The aim of our study was to compare the accuracy of volume calculation between B-mode ultrasonography and volumetric ultrasonography (VUS). METHODS: Between April and May 2007, 27 consecutive patients selected for thyroidectomy were prospectively evaluated. One expert ultrasound operator calculated each thyroid volume with standard B-mode ultrasonography on the basis of the 3 axes of each lobe, and then the patients were analyzed with an offline workstation equipped with volumetric probes (VUS). On the offline workstation, 2 separate blinded operators (VUS1 and VUS2) calculated the thyroid volume with virtual organ computer-aided analysis. Data acquired were then compared with pathologic anatomy (PA). RESULTS: The mean time for B-mode analysis was 6 minutes, whereas VUS analysis needed a mean time of 16.5 minutes. Interobserver variability between the median VUS1 and VUS2 measurements was 0.36 mL (interquartile range [IQR], -0.79 to 0.37 mL; P < .156). The median variability between B-mode ultrasonography and PA was -9.6 mL (IQR, -16.7 to 1.5 mL; P < .001), and that between VUS and PA was -2.87 mL (IQR, -11.97 to 9.51 mL; P = .019). The overall performance of B-mode ultrasonography in comparison with PA was -29.1% (IQR, -47.5% to -5.9%), and that of VUS in comparison with PA was -6.3% (IQR, -26.3 to 13.7%; P < .001). CONCLUSIONS: Volumetric ultrasonography is a valid tool that compares better with PA than does B-mode ultrasonography. |
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Authors:
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Roberto Malago; Mirko D'Onofrio; Marco Ferdeghini; William Mantovani; Chiara Colato; Paolo Brazzarola; Massimiliano Motton; Roberto Pozzi Mucelli |
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Publication Detail:
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Type: Comparative Study; Evaluation Studies; Journal Article |
Journal Detail:
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Title: Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine Volume: 27 ISSN: 1550-9613 ISO Abbreviation: J Ultrasound Med Publication Date: 2008 Dec |
Date Detail:
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Created Date: 2008-11-21 Completed Date: 2009-02-02 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8211547 Medline TA: J Ultrasound Med Country: United States |
Other Details:
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Languages: eng Pagination: 1727-33 Citation Subset: IM |
Affiliation:
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Department of Radiology, Policlinico G. B. Rossi, University of Verona, Verona, Italy. rmalag@sirm.org |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Female Humans Image Interpretation, Computer-Assisted / methods* Imaging, Three-Dimensional / methods* Male Middle Aged Organ Size Reproducibility of Results Sensitivity and Specificity Thyroid Diseases / ultrasonography* Thyroid Gland / ultrasonography* Ultrasonography / methods* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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