Document Detail

Thyroid volume measured by ultrasonography and CT.
MedLine Citation:
PMID:  12100323     Owner:  NLM     Status:  MEDLINE    
PURPOSE: To evaluate measurements of thyroid volume by two different US methods and CT in a blinded design. MATERIAL AND METHODS: Four observers evaluated 27 patients. Observer 1 used US and calculated thyroid volume based on recordings of cross-sections through the gland. Observer 2 used US and calculated the volume of each lobe as a rotation ellipsoid. Observers A and B used CT images and calculated thyroid volume based on recordings of cross-sections through the gland. All measurements were made twice. RESULTS: The median thyroid volume was 81 ml (range 7-470 ml) evaluated by CT. All three methods had fair reproducibility. When correlating the two different methods using US, an r of 0.837 was found. When correlating data from patients without intrathoracic goitre evaluated by US (Observer 1) and CT, r = 0.945. The method based on a rotation ellipsoid systematically produced smaller thyroid volumes than those of the cross-sectional method. Evaluation by US systematically produced smaller thyroid volumes than CT. CONCLUSION: Calculation of thyroid volume based on US recordings of cross-sectional areas is a reproducible method in patients without substernal goitre extension. The US method calculating thyroid volume as a rotation ellipsoid is less reproducible, especially in large goitres. Measurement of thyroid volume using CT should be preferred in goitres with substernal extension.
B Nygaard; T Nygaard; M Court-Payen; L Ingeman Jensen; P Søe-Jensen; K Gerhard Nielsen; M Fugl; L Hegedüs
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Acta radiologica (Stockholm, Sweden : 1987)     Volume:  43     ISSN:  0284-1851     ISO Abbreviation:  Acta Radiol     Publication Date:  2002 May 
Date Detail:
Created Date:  2002-07-08     Completed Date:  2002-08-09     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8706123     Medline TA:  Acta Radiol     Country:  Denmark    
Other Details:
Languages:  eng     Pagination:  269-74     Citation Subset:  IM    
Department of Endocrinology, Herlev Hospital, University of Copenhagen, Denmark.
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MeSH Terms
Aged, 80 and over
Goiter / diagnosis
Middle Aged
Reproducibility of Results
Thyroid Gland / radiography*,  ultrasonography*

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