| Thyroid uptake of MIBG in Sipple's syndrome. | |
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MedLine Citation:
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PMID: 2898364 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The use of the adrenomedullary tracer metaiodobenzylguanidine (MIBG) in the localization of medullary carcinoma of the thyroid (MCT) is based on the embryologic relationship of the APUD cell series. The authors report the results obtained in six patients with MCT: two had Sipple's syndrome and four sporadic forms of the disease. MIBG uptake by the CMT was observed in both cases of Sipple's syndrome and in only one of the other cases. Scintigraphic detection seems to depend on the clinical features, the size of the tumour and also on the part played by its secretory function. MCT would thus appear to be more frequently visualized by MIBG in cases of Sipple's syndrome than in sporadic cases. The procedure therefore seems useful in the diagnosis, follow up and even in the treatment of MCT. |
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Authors:
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R Perdrisot; V Rohmer; J J Lejeune; J C Bigorgne; P Jallet |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: European journal of nuclear medicine Volume: 14 ISSN: 0340-6997 ISO Abbreviation: Eur J Nucl Med Publication Date: 1988 |
Date Detail:
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Created Date: 1988-07-29 Completed Date: 1988-07-29 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 7606882 Medline TA: Eur J Nucl Med Country: GERMANY, WEST |
Other Details:
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Languages: eng Pagination: 37-8 Citation Subset: IM |
Affiliation:
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Laboratoire Joliot Curie, Service de Médecine Nucléaire, CHU, Angers, France. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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3-Iodobenzylguanidine Adult Aged Carcinoma / radionuclide imaging Female Humans Iodine Radioisotopes / diagnostic use* Iodobenzenes / diagnostic use* Male Middle Aged Multiple Endocrine Neoplasia / genetics, radionuclide imaging* Thyroid Neoplasms / radionuclide imaging* |
| Chemical | |
Reg. No./Substance:
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0/Iodine Radioisotopes; 0/Iodobenzenes; 77679-27-7/3-Iodobenzylguanidine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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