Document Detail


Thyroid and steroid hormone regulation of proto-oncogene expression.
MedLine Citation:
PMID:  18411085     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Abstract/OtherAbstract:
In contrast to the established effects of peptide growth factors on specific proto-oncogene expression, the actions of steroid and thyroid hormones are less clearly defined. However, there is increasing evidence that these hormones, acting through structurally related DNA-binding nuclear receptor proteins, influence proto-oncogene expression. This influence may determine the function of steroid and thyroid hormones in regulation of cell proliferation and maturation, and provide insight into the role of these hormones in oncogenesis.
Authors:
J A Franklyn; M C Sheppard
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Trends in endocrinology and metabolism: TEM     Volume:  1     ISSN:  1043-2760     ISO Abbreviation:  Trends Endocrinol. Metab.     Publication Date:    1989 Sep-Oct
Date Detail:
Created Date:  2008-04-15     Completed Date:  2009-12-11     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9001516     Medline TA:  Trends Endocrinol Metab     Country:  United States    
Other Details:
Languages:  eng     Pagination:  35-9     Citation Subset:  -    
Affiliation:
Department of Medicine of the University of Birmingham, Queen Elizabeth Hospital, Birmingham, UK.
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