Document Detail

Thyroid peroxidase prevails over thyroid microsomal and thyroglobulin antibodies in thyroidal and nonthyroidal illnesses.
MedLine Citation:
PMID:  7519499     Owner:  NLM     Status:  MEDLINE    
Autoimmune thyroid disease is usually related to the presence of autoantibodies (TPO, TMA, TGA, TSH-R) in patients' sera. In this study the presence of autoantibodies in the sera of patients with thyroid disease, patients with end-stage renal disease and in several groups of euthyroid subjects have been evaluated (N = 217). The percentages of positive values detected in six groups ranged: 0-47%, 2-94% and 3-100% for TGA, TMA, and TPO, respectively. Autoantibodies were mostly present in the sera of patients with Hashimoto thyroiditis (TPO 100%, TMA 94%, TGA 47%), and sporadically in the control subjects (TPO 4%, TMA 2%, TGA 0%). Authors's results confirm the prevalence of TPO over TGA and TMA in the sera of all investigated groups. The authors did not find changes in ATA levels during methimazole therapy of their patients with Graves' disease. Some of serum autoantibodies were constantly present or absent in spite of remission.
L Lukinac; Z Kusić; D Nöthig-Hus; P Kes
Related Documents :
20350919 - Parathyroidectomy-induced thyroiditis.
22321199 - A score that verifies adherence to a gluten-free diet: a cross-sectional, multicentre v...
19779329 - Hypothyroidism following hemithyroidectomy: a retrospective review.
20394549 - Oxidative stress profile in graves' ophthalmopathy in indian patients.
3043549 - Primary thyroid lymphoma: evaluation with ct.
2448069 - Immunomodulatory effect of the treatment of graves' disease on antigen-specific monocyt...
2317909 - Dissociation of end systole from end ejection in patients with long-term mitral regurgi...
2459669 - A noninvasive pre-atrial activity recording by signal averaging using esophageal electr...
18672349 - Apoe epsilon4 is associated with postictal confusion in patients with medically refract...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Acta medica Croatica : c̆asopis Hravatske akademije medicinskih znanosti     Volume:  48     ISSN:  1330-0164     ISO Abbreviation:  Acta Med Croatica     Publication Date:  1994  
Date Detail:
Created Date:  1994-09-06     Completed Date:  1994-09-06     Revised Date:  2006-04-28    
Medline Journal Info:
Nlm Unique ID:  9208249     Medline TA:  Acta Med Croatica     Country:  CROATIA    
Other Details:
Languages:  eng     Pagination:  63-6     Citation Subset:  IM    
Department of Nuclear Medicine and Oncology, Sestre Milosrdnice University Hospital, Zagreb, Croatia.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Aged, 80 and over
Autoantibodies / analysis*
Autoantigens / immunology*
Child, Preschool
Iodide Peroxidase / immunology*
Iron-Binding Proteins*
Kidney Failure, Chronic / immunology
Middle Aged
Thyroglobulin / immunology*
Thyroid Diseases / immunology*
Reg. No./Substance:
0/Autoantibodies; 0/Autoantigens; 0/Iron-Binding Proteins; 9010-34-8/Thyroglobulin; EC protein, human; EC Peroxidase

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Osteocalcin reference range in a Croatian population sample.
Next Document:  Flow-cytometric lymphocyte phenotyping using automated SimulSET Software gating procedure.