Document Detail


Thyroid hormone extraction by plasma exchange: a study of extraction rate.
MedLine Citation:
PMID:  1292653     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
How to obtain an optimal efficiency of plasma exchanges in the treatment of severe hyperthyroidism has not been defined. In order to evaluate how long the exchanges must be continued to be fully effective in extracting thyroid hormones, we evaluated the extraction rate by repeated plasma sampling in two hyperthyroid patients and three euthyroid subjects who underwent a total of seven exchanges. Plasma concentrations of thyroid hormones were also determined just before, just after, and 24 hours following the exchange. The hormonal removal rate did not fall dramatically during the exchange, so that its efficiency--in terms of hormone extraction--depends closely on its duration. The determination of plasma thyroid hormone concentrations after the exchange does not appear to be useful in evaluating the thyroid hormone loss since these concentrations may not change in spite of the hormonal extraction.
Authors:
H Puy; J Lamoril; J M Marcelli; J D Lalau; X Debussche; J Quichaud; G Desmet
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Biomedicine & pharmacotherapy = Biomédecine & pharmacothérapie     Volume:  46     ISSN:  0753-3322     ISO Abbreviation:  Biomed. Pharmacother.     Publication Date:  1992  
Date Detail:
Created Date:  1993-04-07     Completed Date:  1993-04-07     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8213295     Medline TA:  Biomed Pharmacother     Country:  FRANCE    
Other Details:
Languages:  eng     Pagination:  413-7     Citation Subset:  IM    
Affiliation:
Laboratoire d'Hormonologie, Hôpital Sud, Amiens, France.
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MeSH Terms
Descriptor/Qualifier:
Humans
Hyperthyroidism / blood,  therapy
Plasma Exchange / methods*
Thyroid Hormones / blood,  isolation & purification*
Time Factors
Chemical
Reg. No./Substance:
0/Thyroid Hormones

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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