Document Detail

Thyroid hormone changes in obese subjects during fasting and a very-low-calorie diet.
MedLine Citation:
PMID:  7275468     Owner:  NLM     Status:  MEDLINE    
Total fasting was compared with VLCD (1.28 MJ, 300 kcal/day; 56 g protein, 12 g CHO) in 14 euthyroid obese patients, selected as matched pairs, over a period of 28 days. The weight loss was significantly greater during fasting than during the VLCD (16.5 kg vs. 12.7 kg). The basal metabolic rate of (BMR) showed a significant decrease (25 per cent) during total fasting, but was unchanged with the VLCD. With both diets there was a transient increase in T4, FT4 and FT4I, and a tendency for TSH to decrease. There was a decrease in T3 and a transient increase in rT3. Nitrogen balance was attained in five of seven patients on the VLCD after four weeks.
U Rabast; A Hahn; C Reiners; M Ehl
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Publication Detail:
Type:  Clinical Trial; Controlled Clinical Trial; Journal Article    
Journal Detail:
Title:  International journal of obesity     Volume:  5     ISSN:  -     ISO Abbreviation:  Int J Obes     Publication Date:  1981  
Date Detail:
Created Date:  1981-11-22     Completed Date:  1981-11-22     Revised Date:  2014-06-03    
Medline Journal Info:
Nlm Unique ID:  7703240     Medline TA:  Int J Obes     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  305-11     Citation Subset:  IM    
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MeSH Terms
Basal Metabolism
Body Weight
Diet, Reducing*
Nitrogen / metabolism
Obesity / blood*,  diet therapy
Thyroid Hormones / blood*
Time Factors
Reg. No./Substance:
0/Thyroid Hormones; N762921K75/Nitrogen

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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