| Thyroid gland invasion in laryngopharyngeal squamous cell carcinoma: Prevalence, endoscopic and CT predictors. | |
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MedLine Citation:
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PMID: 21798840 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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OBJECTIVES: The authors studied the prevalence of histological thyroid gland invasion in laryngopharyngeal cancer and the preoperative endoscopic and CT signs predictive of this invasion. PATIENTS AND METHODS: Retrospective study of patients with laryngopharyngeal squamous cell carcinoma (T3 and T4) treated by total laryngectomy or total laryngopharyngectomy associated with concomitant total thyroidectomy or ipsilateral lobectomy and isthmectomy. RESULTS: Eighty-seven patients were included. Eleven patients (12.6%) presented thyroid gland invasion. Subglottic tumour extension greater than or equal to 10mm (P=0.008) and cricoid cartilage destruction on CT (P=0.001) were statistically correlated with histological thyroid gland invasion. An intact appearance of the laryngeal cartilages on CT was associated with a low probability of thyroid gland invasion. CONCLUSION: Thyroid gland invasion must not be underestimated in patients with advanced laryngopharyngeal cancer. Preoperative CT is an essential part of the preoperative work-up. Thyroidectomy must not be performed systematically. |
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Authors:
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L Gaillardin; P Beutter; J-P Cottier; F Arbion; S Morinière |
Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-7-26 |
Journal Detail:
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Title: European annals of otorhinolaryngology, head and neck diseases Volume: - ISSN: 1879-7296 ISO Abbreviation: - Publication Date: 2011 Jul |
Date Detail:
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Created Date: 2011-7-29 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101531465 Medline TA: Eur Ann Otorhinolaryngol Head Neck Dis Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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Copyright © 2011 Elsevier Masson SAS. All rights reserved. |
Affiliation:
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Service ORL et chirurgie cervicofaciale, hôpital Bretonneau, CHRU de Tours, boulevard Tonnellé, 37000 Tours, France. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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