| Thyroid function and pregnancy: before, during and beyond. | |
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MedLine Citation:
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PMID: 21126112 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
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Thyroid disturbances are common in women during the reproductive years of their lives. Autoimmunity and altered iodine status together account for a high proportion of the abnormalities. Autoimmune thyroid disease is present in around 4% of young females, and up to 15% are at risk because they are thyroid antibody-positive. There is a strong relationship between thyroid immunity on the one hand and infertility, miscarriage, and thyroid disturbances in pregnancy and postpartum on the other hand. Suboptimal iodine status affects a large proportion of the world's population, and pregnancy further depletes iodine stores. There is controversy surrounding the degree to which iodine should be supplemented and the duration of supplementation. Recent studies have helped to clarify the relationship between maternal thyroid status and neuropsychological development of the child. The role of other environmental factors including smoking and selenium status is also now recognised. Universal screening for thyroid hormone abnormalities is not routinely recommended at present. However, measurement of thyroid function and autoantibodies should certainly be considered in those who are at high risk of thyroid disease and in those whose pregnancy is otherwise high risk. The practicing clinician needs to be aware of the thyroid changes which accompany pregnancy. |
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Authors:
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R L Kennedy; U H Malabu; G Jarrod; P Nigam; K Kannan; A Rane |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology Volume: 30 ISSN: 1364-6893 ISO Abbreviation: J Obstet Gynaecol Publication Date: 2010 |
Date Detail:
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Created Date: 2010-12-03 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8309140 Medline TA: J Obstet Gynaecol Country: England |
Other Details:
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Languages: eng Pagination: 774-83 Citation Subset: IM |
Affiliation:
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James Cook University School of Medicine, Queensland, Australia. lee.kennedy@jcu.edu.au |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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