Document Detail

Thyroid function in dietary amenorrhoea.
MedLine Citation:
PMID:  589804     Owner:  NLM     Status:  MEDLINE    
Abnormalities of thyroid function are well known to occur in anorexia nervosa. A commoner problem is the patient with secondary amenorrhoea due to weight loss, who does not have true anorexia nervosa. Eight such patients were studied and compared to a normal control group. Total and free thyroxine, total and free triiodothyronine were found to be significantly lower in the amenorrhoea patients. No difference in basal thyroid stimulating hormone or reverse triiodothyronine levels were found. In three of four patients who had thyrotrophin releasing hormone tests performed a prolonged response was found. These results indicate that abnormal thyroid function tests may be found in this milder form of the disease. In addition, the normal reverse triiodothyronine levels suggest the possibility of two mechanisms existing, whereby T3 levels may be lowered in nutritional disorders.
J E Thomson; S G Baird; J A Thomson
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Clinical endocrinology     Volume:  7     ISSN:  0300-0664     ISO Abbreviation:  Clin. Endocrinol. (Oxf)     Publication Date:  1977 Nov 
Date Detail:
Created Date:  1978-02-18     Completed Date:  1978-02-18     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0346653     Medline TA:  Clin Endocrinol (Oxf)     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  383-8     Citation Subset:  IM    
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MeSH Terms
Amenorrhea / etiology,  physiopathology*
Nutrition Disorders / complications,  physiopathology*
Thyroid Gland / physiopathology*
Thyrotropin / blood
Thyroxine / blood
Triiodothyronine / blood
Reg. No./Substance:
6893-02-3/Triiodothyronine; 7488-70-2/Thyroxine; 9002-71-5/Thyrotropin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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