| Thyroid dysfunction following therapeutic external radiation to head and neck cancer. | |
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MedLine Citation:
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PMID: 21545210 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Aim: The aim of the present study was to evaluate changes in thyroid function in patients with head and neck cancer treated with external beam radiotherapy (EBRT). Materials and Methods: This prospective study was conducted on ninety patients with non-thyroid head and neck cancer who were referred to the department of radiotherapy. Thyroid function tests were conducted before, midway during and after EBRT, with follow up at monthly intervals up to 6 months after the completion of therapy. Results: Serum T3 and T4 levels were decreased at completion of EBRT and remained so after 6 months follow up. However, serum TSH levels did not significantly vary. Conclusion: EBRT to the neck region for treatment of head and neck cancer induces hypothyroidism and therefore utmost care must be taken to exclude the thyroid from radiation beams without sparing the tumor as far as possible. The clinical protocol in such cases should include monitoring of T3, T4 and TSH levels during and after the EBRT. |
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Authors:
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Arun Chougule; Bhawani Kochar |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Asian Pacific journal of cancer prevention : APJCP Volume: 12 ISSN: 1513-7368 ISO Abbreviation: Asian Pac. J. Cancer Prev. Publication Date: 2011 |
Date Detail:
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Created Date: 2011-05-06 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101130625 Medline TA: Asian Pac J Cancer Prev Country: Thailand |
Other Details:
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Languages: eng Pagination: 443-5 Citation Subset: IM |
Affiliation:
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Radiation Physics and Dean Faculty of Paramedical Sciences, S.M.S. Medical College and Hospital, Jaipur, India E-mail: arunchougle@rediffmail.com, arunchougule11@gmail.com. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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