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Thyroid disorders in Chronic Heart Failure: from prognostic set-up to therapeutic management.
MedLine Citation:
PMID:  23369135     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Thyroid hormones have relevant activity at cardiac and vascular level, by influencing heart rate, myocardial excitability as well as inotropic and lusitropic status, systemic vascular resistance and blood pressure. Moreover, they interact with neuro-hormonal systems such as sympathetic nervous system and renin-angiotensin-aldosterone system thus also indirectly influencing cardiovascular function. Due to these effects, both hypothyroidism and hyperthyroidism, either in their overt or subclinical, can have an unfavourable impact in the setting of cardiovascular diseases. The aim of this review was to focus on the prognostic consequences of thyroid disorders in heart failure patients. Moreover, the therapeutical approach and the possible beneficial effects of restoring euthyroidism have been reviewed.
Authors:
Vincenzo Triggiani; Massimo Iacoviello
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-1-15
Journal Detail:
Title:  Endocrine, metabolic & immune disorders drug targets     Volume:  -     ISSN:  2212-3873     ISO Abbreviation:  Endocr Metab Immune Disord Drug Targets     Publication Date:  2013 Jan 
Date Detail:
Created Date:  2013-2-1     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101269157     Medline TA:  Endocr Metab Immune Disord Drug Targets     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Endocrinology and Metabolic Diseases University of Bari "Aldo Moro" Address: via Repubblica Napoletana n. 7, 70123, Bari, Italy. v.triggiani@endo.uniba.it.
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