| Thyroid-associated orbitopathy developed during hormone replacement therapy. | |
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MedLine Citation:
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PMID: 11453868 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Thyroid-associated orbitopathy (TAO) developed in relation to estrogen combined with progesterone therapy has not been reported previously. We report a case of a 56-year-old postmenopausal woman who during estrogen/progesterone treatment developed signs and symptoms of orbitopathy. The patient had no previous history of autoimmune- or thyroid disorders. The initial eye symptoms disappeared after withdrawal of hormone replacement therapy. Five years later estrogen/progesterone treatment was re-instituted. The patient had relapse of orbitopathy. The hormones were discontinued and the eye symptoms disappeared again. This suggests that estrogen and/or progesterone could be of some pathogenetic importance in the induction of orbitopathy |
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Authors:
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C G Øgard; C Øgard; T P Almdal |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Acta ophthalmologica Scandinavica Volume: 79 ISSN: 1395-3907 ISO Abbreviation: Acta Ophthalmol Scand Publication Date: 2001 Aug |
Date Detail:
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Created Date: 2001-07-16 Completed Date: 2001-09-13 Revised Date: 2008-03-17 |
Medline Journal Info:
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Nlm Unique ID: 9507578 Medline TA: Acta Ophthalmol Scand Country: Denmark |
Other Details:
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Languages: eng Pagination: 426-7 Citation Subset: IM |
Affiliation:
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Department of Endocrinology and Department of Ophthalmology, Herlev Hospital, University of Copenhagen, Denmark. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Drug Therapy, Combination Estrogens / adverse effects* Female Graves Disease / chemically induced* Hormone Replacement Therapy / adverse effects* Humans Middle Aged Orbital Diseases / chemically induced* Progesterone / adverse effects* Recurrence |
| Chemical | |
Reg. No./Substance:
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0/Estrogens; 57-83-0/Progesterone |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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