Document Detail


Thyroid abnormalities in dermatitis herpetiformis. Prevalence of clinical thyroid disease and thyroid autoantibodies.
MedLine Citation:
PMID:  3966757     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We studied thyroid abnormalities in 50 patients with dermatitis herpetiformis. Two patients had a history of hyperthyroidism, and 5 had hypothyroidism and were on thyroid replacement therapy. Three patients had had thyroidectomies for nodules, and 5 had asymptomatic goiter. Two patients were clinically euthyroid with elevated thyrotrophin and low normal thyroxine levels, indicating early thyroid insufficiency. Thyroid microsomal antibodies were seen in 38% of patients with dermatitis herpetiformis compared to 12% of controls. The presence of clinical or serologic thyroid abnormalities in 26 of 50 patients shows a significant but unexplained association between dermatitis herpetiformis and thyroid disease.
Authors:
M J Cunningham; J J Zone
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Annals of internal medicine     Volume:  102     ISSN:  0003-4819     ISO Abbreviation:  Ann. Intern. Med.     Publication Date:  1985 Feb 
Date Detail:
Created Date:  1985-02-11     Completed Date:  1985-02-11     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  0372351     Medline TA:  Ann Intern Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  194-6     Citation Subset:  AIM; IM    
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Aged
Autoantibodies / analysis*
Dermatitis Herpetiformis / complications*,  drug therapy,  immunology
Female
Humans
Male
Microsomes / immunology
Middle Aged
Sulfones / adverse effects,  therapeutic use
Thyroid Diseases / complications*,  immunology
Thyroid Gland / immunology*
Thyroid Hormones / blood
Grant Support
ID/Acronym/Agency:
1R01 AM 28412-01/AM/NIADDK NIH HHS; RR-64/RR/NCRR NIH HHS
Chemical
Reg. No./Substance:
0/Autoantibodies; 0/Sulfones; 0/Thyroid Hormones

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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