Document Detail

Thyroid storm with multiorgan failure.
MedLine Citation:
PMID:  20146655     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Thyroid storm is a rare and potentially fatal condition. Various unusual presentations in patients with thyroid storm have been described but multiorgan dysfunction is uncommonly seen. SUMMARY: We describe a 35-year-old patient with a history of Graves' disease who was diagnosed with thyroid storm at 2 weeks postpartum. This was complicated by acute liver failure, acute kidney injury, severe lactic acidosis, disseminated intravascular coagulation, and heart failure with acute pulmonary edema. The multiorgan dysfunction was reversed by prompt institution of antithyroid drugs and supportive management in the intensive care unit. CONCLUSION: Thyroid storm is a medical emergency. One of the challenges lies in recognizing its varied presentations. Early diagnosis and appropriate treatment is important to prevent the catastrophic outcomes associated with this condition.
Hui Wen Chong; Kay Choong See; Jason Phua
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Thyroid : official journal of the American Thyroid Association     Volume:  20     ISSN:  1557-9077     ISO Abbreviation:  Thyroid     Publication Date:  2010 Mar 
Date Detail:
Created Date:  2010-03-01     Completed Date:  2010-05-25     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9104317     Medline TA:  Thyroid     Country:  United States    
Other Details:
Languages:  eng     Pagination:  333-6     Citation Subset:  IM    
Division of Respiratory and Critical Care Medicine, Department of Medicine, National University Hospital, Singapore, Singapore.
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MeSH Terms
Antithyroid Agents / therapeutic use*
Graves Disease / complications
Multiple Organ Failure / complications,  drug therapy*
Patient Compliance
Thyroid Crisis / complications,  drug therapy*
Treatment Outcome
Reg. No./Substance:
0/Antithyroid Agents

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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