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Thyroid Stiffness Assessment by Acoustic Radiation Force Impulse Elastography (ARFI).
MedLine Citation:
PMID:  21321841     Owner:  NLM     Status:  Publisher    
PURPOSE: To evaluate and compare the values of thyroid tissue elasticity in subjects without known thyroid pathology, in patients with Graves' disease and with chronic autoimmune thyroiditis (CAT). PATIENTS AND METHODS: We performed a prospective study that included 74 subjects, 23 without thyroid pathology, 29 with Graves' disease and 22 with CAT (diagnosed by specific tests). In all patients, 10 elastographic measurements were performed in the right thyroid lobe (RTL) and 10 in the left thyroid lobe (LTL) using a 2 - 6 MHz convex probe. Median values were calculated for each thyroid lobe, measured in meters/second (m/sec). We calculated a mean ARFI value from measurements made in the RTL and LTL. RESULTS: Thyroid stiffness was statistically significant lower in normal subjects vs. those with Graves' disease (2.07 ± 0.44 m/sec vs. 2.82 ± 0.47 m/sec, p < 0.001) and with CAT (2.07 ± 0.44 m/sec vs. 2.49 ± 0.48 m/sec, p = 0.004). We also found a statistically significant difference between subjects without thyroid pathology and those with autoimmune thyroid pathology (Graves' disease and CAT) (2.07 ± 0.44 m/sec vs. 2.68 ± 0.50 m/sec, p < 0.001). CONCLUSION: ARFI seems to be a useful method for the evaluation of diffuse thyroid gland pathology and is able to predict with sufficient accuracy the presence of thyroid diffuse diseases (AUROC = 0.80).
I Sporea; M Vlad; S Bota; R L Sirli; A Popescu; M Danila; M Sendroiu; I Zosin
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-2-14
Journal Detail:
Title:  Ultraschall in der Medizin (Stuttgart, Germany : 1980)     Volume:  -     ISSN:  1438-8782     ISO Abbreviation:  -     Publication Date:  2011 Feb 
Date Detail:
Created Date:  2011-2-15     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8303585     Medline TA:  Ultraschall Med     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
© Georg Thieme Verlag KG Stuttgart · New York.
Gastroenterology, University of Medicine and Pharmacy Timisoara.
Vernacular Title:
Bewertung der Schilddrüsensteifheit durch die "Acoustic Radiation Force Impulse"-Elastografie (ARFI).
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