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Thymomas II: A Clinicopathologic Correlation of 250 Cases With a Proposed Staging System With Emphasis on Pathologic Assessment.
MedLine Citation:
PMID:  22338058     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
We present 250 cases of thymomas with emphasis on their clinical staging and follow-up. The patients were 120 males and 130 females between the ages of 13 and 92 years. Surgical resection was performed and histopathologic material evaluated in every case. Grossly, the tumors resected varied in size from 3 to 20 cm in greatest diameter. According to our proposed staging system, 31 cases were stage 0, 128 were stage I, 70 stage II, and 21 stage III at the time of resection. Histologically, approximately 53% of thymomas were of mixed histologic types. Follow-up information ranging from 1 to 16 years was obtained, showing significant statistical P values of .044 and .016 for overall and recurrence-free survival, respectively. We consider that our proposed staging system offers better stratification of cases and improved histologic definitions for proper staging of cases of thymoma.
Authors:
Cesar A Moran; Garrett Walsh; Saul Suster; Larry Kaiser
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  American journal of clinical pathology     Volume:  137     ISSN:  1943-7722     ISO Abbreviation:  Am. J. Clin. Pathol.     Publication Date:  2012 Mar 
Date Detail:
Created Date:  2012-02-16     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0370470     Medline TA:  Am J Clin Pathol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  451-61     Citation Subset:  AIM; IM    
Affiliation:
Dept of Pathology, M.D. Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030.
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