Document Detail


Thumb involvement in Raynaud's phenomenon as an indicator of underlying connective tissue disease.
MedLine Citation:
PMID:  20194444     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: To conduct a retrospective study to assess whether the degree of thumb involvement differs between primary Raynaud's phenomenon (PRP) and secondary Raynaud's phenomenon (SRP). METHODS: Thermography images from all patients attending Salford Royal Hospital and referred for thermography for assessment of RP between 2004 and 2006 were retrospectively reviewed. A distal dorsal difference (DDD) of -1 degrees C or less between the fingertips and dorsum of the hand (fingers cooler) at 23 degrees C was considered clinically relevant. The worse score (the lower score, i.e., the more negative value) from each pair of digits was considered for analysis. RESULTS: One hundred seventy patients fulfilled the study criteria. DDD at 23 degrees C for the thumbs were significantly higher (digital tips warmer) compared with other digits (p < 0.001) in both PRP and SRP. All digits were significantly warmer in PRP compared to SRP with the exception of the thumbs. The proportion of patients with clinically relevant involvement of thumbs was significantly higher in SRP compared to PRP (p = 0.003) and this difference was more pronounced in the thumbs compared with other digits. CONCLUSION: Although the median temperature gradient along the thumb was not significantly different between SRP and PRP, the thumb is more likely to be involved in SRP than in PRP. Thumb involvement is one of a number of clinical indicators that should alert the clinician to the possibility of an underlying connective tissue disease/disorder.
Authors:
Batsi Chikura; Tonia Moore; Joanne Manning; Andy Vail; Ariane L Herrick
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Publication Detail:
Type:  Journal Article     Date:  2010-03-01
Journal Detail:
Title:  The Journal of rheumatology     Volume:  37     ISSN:  0315-162X     ISO Abbreviation:  J. Rheumatol.     Publication Date:  2010 Apr 
Date Detail:
Created Date:  2010-04-02     Completed Date:  2010-06-22     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7501984     Medline TA:  J Rheumatol     Country:  Canada    
Other Details:
Languages:  eng     Pagination:  783-6     Citation Subset:  IM    
Affiliation:
Department of Rheumatology, Lincoln County Hospital, Lincoln, UK. batsi@doctors.org.uk
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Aged
Aged, 80 and over
Analysis of Variance
Connective Tissue Diseases / diagnosis*
Diagnosis, Differential
Female
Humans
Male
Middle Aged
Raynaud Disease / diagnosis*
Retrospective Studies
Thermography
Thumb*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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