Document Detail

Thrombus within an aortic aneurysm does not reduce pressure on the aneurysmal wall.
MedLine Citation:
PMID:  10709063     Owner:  NLM     Status:  MEDLINE    
PURPOSE: The role of thrombus within an aneurysm in relation to the risk of rupture is controversial. In literature, reports describing reduction and increase of rupture risk can be found. In the era of endovascular treatment of abdominal aortic aneurysms, a possible reduction of risk of rupture by the presence of thrombus within the aneurysmal sac can be important in relation to the location of an endoleak to the aneurysmal wall and in relation to the effect of the thrombosis of the endoleak, either spontaneously or by intervention.
METHODS: In nine patients who underwent operation for an infrarenal aortic aneurysm by open procedure at the level of the thickest thrombus lining, the pressure within the aneurysmal thrombus (just inside the aneurysmal wall) was measured and compared with the systemic pressure.
RESULTS: Pressure within systemic circulation and aneurysmal thrombus correlated well for the mean pressure (r = 0.90; P <.001) and for pulse pressure (r = 0.74; P <.01) Also, there was agreement between the levels of the mean pressure. Conduction of mean and pulse pressure to the aneurysmal wall was not related to the thickness of the thrombus at the level of the pressure measurement (r = 0.18 and r = 0.08, respectively).
CONCLUSION: We conclude that thrombus within the aneurysm does not reduce both the mean and the pulse pressure near the aneurysmal wall and thus will not reduce the risk of rupture of the aneurysm.
G W Schurink; J M van Baalen; M J Visser; J H van Bockel
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of vascular surgery     Volume:  31     ISSN:  0741-5214     ISO Abbreviation:  J. Vasc. Surg.     Publication Date:  2000 Mar 
Date Detail:
Created Date:  2000-04-25     Completed Date:  2000-04-25     Revised Date:  2012-10-03    
Medline Journal Info:
Nlm Unique ID:  8407742     Medline TA:  J Vasc Surg     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  501-6     Citation Subset:  IM    
Department of Surgery, Section Vascular Surgery, Leiden University Medical Center, Leiden, The Netherlands.
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MeSH Terms
Aortic Aneurysm, Abdominal / physiopathology*,  surgery
Aortic Rupture / epidemiology
Risk Assessment
Thrombosis / physiopathology*
Comment In:
J Vasc Surg. 2001 Mar;33(3):660-1   [PMID:  11241148 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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