Document Detail

Thrombus aspiration in a series of patients with stable or unstable angina pectoris and lesion-site thrombus formation.
MedLine Citation:
PMID:  20862237     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Background. In acute myocardial infarction, thrombus aspiration prior to percutaneous coronary interventions (PCI) is often beneficial, but this approach has never been studied in patients without acute myocardial infarction. The aim of this retrospective study is to shed light on that topic based on our initial experience with manual thrombus aspiration in patients with stable or unstable angina pectoris and angiographic evidence of lesion-site thrombus. Methods. We assessed the feasibility (thrombus aspiration without predilatation) of this approach; in addition, we determined angiographic coronary flow and myocardial blush grade. Results. During 33 months in which a total of 4725 PCI were performed in our centre, manual thrombus aspiration was attempted in 14 patients with stable or unstable angina pectoris with angiographic evidence of thrombus. In nine of these 14 patients, the aspiration catheter could be advanced into the lesion without predilatation; in eight patients visible thrombus was obtained. The corrected TIMI frame count improved during the entire interventional procedure (21.1±11.2 vs. 12.8±5.9 frames; p=0.015). Myocardial blush grade, which overall improved during PCI (p<0.001), tended to show greater improvement in patients in whom thrombus aspiration could be achieved (1.6±0.9 vs. 0.7±0.5; p=0.06). Conclusions. Preliminary evidence suggests that manual thrombus aspiration may occasionally be considered in selected patients without acute myocardial infarction but with angiographic evidence of lesion-site thrombus. Nevertheless, prospective studies are required to clearly define the role of this approach in clinical practice. (Neth Heart J 2010;18:423-9.).
J A J M Hermens; G K van Houwelingen; F H A F de Man; H W Louwerenburg; C von Birgelen
Related Documents :
14511297 - Central venous catheter-related thrombosis presenting as superior vena cava syndrome in...
23663817 - Impact of timing and dose of mesenchymal stromal cell therapy in a preclinical model of...
17982977 - Peripheral primitive neuroectodermal tumour of left ventricular wall origin: a rare case.
7981537 - The problems of surgical treatment for cardiac myxoma and associated lesions.
12216437 - Hydatid of morgagni with torsion diagnosed during cesarean delivery. a case report.
20092827 - Pleomorphic ventricular tachycardia originating from purkinje fiber network of left ant...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation     Volume:  18     ISSN:  1876-6250     ISO Abbreviation:  Neth Heart J     Publication Date:  2010 Sep 
Date Detail:
Created Date:  2010-09-23     Completed Date:  2011-07-14     Revised Date:  2013-05-29    
Medline Journal Info:
Nlm Unique ID:  101095458     Medline TA:  Neth Heart J     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  423-9     Citation Subset:  -    
Department of Cardiology, Thoraxcentrum Twente, Medisch Spectrum Twente, Enschede, the Netherlands.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Early versus late ST-segment resolution and clinical outcomes after percutaneous coronary interventi...
Next Document:  Endovascular stenting for aortic (re)coarctation in adults.