Document Detail


Thrombus formation during percutaneous closure of an atrial septal defect with an Amplatzer septal occluder.
MedLine Citation:
PMID:  21841876     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Percutaneous closure of an ostium secundum-type atrial septal defect is typically a safe and effective therapeutic option in the presence of significant shunting or paradoxical embolism. Infrequently, however, periprocedural sequelae occur.Herein, we report the cases of 2 patients, each of whom underwent transcatheter closure of an atrial septal defect with the use of an Amplatzer Septal Occluder under transesophageal echocardiographic guidance. In both patients, acute thrombi formed periprocedurally, despite preprocedural anticoagulation. In patient 1, the infusion of unfractionated heparin for 24 hours prevented the recurrence of thrombus; in patient 2, the thrombus was isolated under the arm of the occluder, and unfractionated heparin was infused. Both patients were asymptomatic and without detectable thrombus after the procedure and at follow-up. These reports highlight a rare early sequela and the importance of transesophageal echocardiographic monitoring during the percutaneous closure of an atrial septal defect.
Authors:
Hikmet Yorgun; Ugur Canpolat; Ergun Baris Kaya; Kudret Aytemir; Ali Oto
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Texas Heart Institute journal / from the Texas Heart Institute of St. Luke's Episcopal Hospital, Texas Children's Hospital     Volume:  38     ISSN:  1526-6702     ISO Abbreviation:  Tex Heart Inst J     Publication Date:  2011  
Date Detail:
Created Date:  2011-08-15     Completed Date:  2012-01-05     Revised Date:  2012-01-27    
Medline Journal Info:
Nlm Unique ID:  8214622     Medline TA:  Tex Heart Inst J     Country:  United States    
Other Details:
Languages:  eng     Pagination:  427-30     Citation Subset:  IM    
Affiliation:
Department of Cardiology, Hacettepe University, 06100 Ankara, Turkey.
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MeSH Terms
Descriptor/Qualifier:
Adult
Anticoagulants / administration & dosage
Drug Administration Schedule
Echocardiography, Transesophageal
Female
Heart Catheterization / adverse effects*,  instrumentation*
Heart Septal Defects, Atrial / therapy*,  ultrasonography
Heparin / administration & dosage
Humans
Infusions, Parenteral
Male
Middle Aged
Septal Occluder Device*
Thrombosis / drug therapy,  etiology*,  ultrasonography
Treatment Outcome
Ultrasonography, Interventional
Chemical
Reg. No./Substance:
0/Anticoagulants; 9005-49-6/Heparin
Comments/Corrections
Erratum In:
Tex Heart Inst J. 2011;38(5):612
Note: Dosage error in article text

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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