|Thrombus extraction catheters vs. angiojet rheolytic thrombectomy in thrombotic lesions/SV grafts.|
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|PMID: 22920486 Owner: NLM Status: MEDLINE|
|Primary percutaneous coronary intervention, (pPCI), of native coronaries and saphenous vein grafts (SVGs), is the recommended reperfusion strategy for STEMI, and an early invasive approach is recommended for high risk patients with UA/NSTEMI. Although PCI effectively restores flow in the infarct related artery/culprit vessel in both situations, myocardial perfusion often remains suboptimal due to microvascular obstruction, partly attributed to distal embolization of thrombus. Hence, thrombectomy (manual or mechanical), prior to stenting may further reduce hard clinical end points in patients with ACS. This article discusses accumulated evidence regarding the safety and effectiveness of thrombectomy in culprit native coronaries and SVGs in such patients, as well as possible strategies for maximizing its benefits relative to the size of the thrombotic burden.|
|Dimitrios Alexopoulos; Periklis A Davlouros|
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|Type: Comparative Study; Journal Article; Review|
|Title: Current cardiology reviews Volume: 8 ISSN: 1875-6557 ISO Abbreviation: Curr Cardiol Rev Publication Date: 2012 Aug|
|Created Date: 2012-12-05 Completed Date: 2013-05-10 Revised Date: 2013-08-12|
Medline Journal Info:
|Nlm Unique ID: 101261935 Medline TA: Curr Cardiol Rev Country: United Arab Emirates|
|Languages: eng Pagination: 202-8 Citation Subset: IM|
|Cardiology Department, Patras University Hospital, Rion 26504, Greece. firstname.lastname@example.org|
|APA/MLA Format Download EndNote Download BibTex|
Coronary Occlusion / surgery
Coronary Thrombosis / surgery*
Graft Occlusion, Vascular / surgery
Myocardial Infarction / surgery*
Percutaneous Coronary Intervention / instrumentation*, methods
Saphenous Vein / transplantation
Thrombectomy / instrumentation*, methods
Journal ID (nlm-ta): Curr Cardiol Rev
Journal ID (iso-abbrev): Curr Cardiol Rev
Journal ID (publisher-id): CCR
Publisher: Bentham Science Publishers
© 2012 Bentham Science Publishers
Received Day: 14 Month: 2 Year: 2012
Revision Received Day: 7 Month: 3 Year: 2012
Accepted Day: 14 Month: 3 Year: 2012
Electronic publication date: Month: 8 Year: 2012
Print publication date: Month: 8 Year: 2012
Volume: 8 Issue: 3
First Page: 202 Last Page: 208
PubMed Id: 22920486
Publisher Id: CCR-8-202
|Thrombus Extraction Catheters vs. Angiojet Rheolytic Thrombectomy in Thrombotic Lesions/SV Grafts|
|Periklis A Davlouros|
|Cardiology Department, Patras University Hospital, Patras, Greece
|*Address correspondence to this author at the Cardiology Department, Patras University Hospital, Rion 26504, Greece; Tel: +302610999281; E-mail: email@example.com
Contemporary management of patients with ST-elevation myocardial infarction, (STEMI), with primary angioplasty, (pPCI), is the recommended reperfusion strategy for STEMI . In high risk patients with non-STEMI acute coronary syndromes (ACS), an early invasive approach is also strongly recommended . Although PCI restores flow in the infarct related artery in most patients with ACS, myocardial perfusion often remains suboptimal due to microvascular obstruction, partly attributed to distal embolization of thrombus [3, 4]. This in turn, is associated with larger infarct size, increased early and late mortality, and higher rates of arrhythmia and heart failure. Hence, devices designed to remove thrombus (like manual aspiration or mechanical thrombectomy catheters), or prevent distal embolizaton, have been developed during the last 10 years (Fig. 1).
Aspiration catheters usually consist of a monorail dual lumen system with a distal radiopaque tip marker and a proximal luer lock port attached to a syringe for hand-powered suction to remove thrombus. (Figs. 1, 2, 3). Manual thrombectomy is simple, and is generally considered safe when performed according to a standard technique, which includes avoiding balloon pre-dilatation, aspirating with initial antegrade advancement of the catheter, and performing multiple passages until disappearance of visible thrombus .
The ESC Guidelines on myocardial revascularization list AT during pPCI in STEMI, as a Class IIa, level of evidence-A, indication , whereas a Class IIa indication with level of evidence-B, is listed in the AHA/ACC Guidelines on STEMI management [7, 8]. These recommendations resulted from a large number of studies with various devices showing mainly an improvement in surrogate procedural end-points. The EXPIRA study, compared the Export aspiration catheter (Medronic Vascular, USA), versus pPCI alone, and showed that the former resulted in a significant improvement of myocardial blush grade (MBG) and complete ST-segment elevation resolution (STR) . This small study (175 patients), involved MRI imaging and showed that the extend of microvascular obstruction was less in the acute phase with aspiration, leading to a smaller infarct size at 3 months. The landmark TAPAS study in patients with STEMI, found that AT with the Export catheter resulted in improved myocardial reperfusion and more frequent complete STR, compared with conventional PCI . Aspiration was able to be performed in 90% of patients and was successful (judged by histopathological evidence of atherothrombotic material) in 72.9%. Patients with better MBG had fewer adverse events at 30 days, and this was regarded as indirect evidence of the beneficial role of AT . Indeed, at 1 year cardiac death was significantly reduced by 46% in the AT group . Despite its impressive results, TAPAS was a single centre study, not powered to detect differences in clinical endpoints . Since then three large meta-analyses have consecutively shown a mortality reduction with AT compared to pPCI alone [13-15]. In contrast, a recent Bayesian meta-analysis of 16 trials showed that AT was associated with fewer distal emboli, less no-reflow, more frequent TIMI 3 flow post-PCI, more STR >50%, and more MBG-3, but no significant 30-day mortality reduction [16, 17].
The most frequently used MT devices are the AngioJet (Medrad Interventional/Possis, Medical, Minneapolis, Minnesota), providing rheolytic thrombectomy (RT), and the X-Sizer system (eV3, White Bear Lake, Minnesota), (Fig. 1). With both devices, multiple passes across the lesion should be performed until optimal angiographic result. Most of the studies in native coronaries have been performed with RT. A study of 100 patients showed that initial RT was associated with a lower corrected TIMI frame count, and a smaller infarct size compared to direct stenting alone . Others have also shown improvement in surrogate procedural end-points when using RT to treat stent thrombosis . A larger study, the AiMI trial, enrolling 480 patients with STEMI (<12 hours) showed a lower final TIMI-3 flow, and higher infarct size and 30-day MACE in the RT group compared with pPCI alone . This disappointing result was attributed to the extremely low mortality rate in the PCI alone arm of the study and to technical details. Balloon pre-dilatation was usually performed before RT, and the AngioJet catheter was advanced beyond the occlusion before activation, which both may have promoted distal embolization. A Bayesian metaanalysis comparing RT (11 studies, 1.018 patients) versus PCI (81 studies, 2.076 patients) in AMI, found similar odds of short-term mortality, MACE, and TIMI-3 flow, despite the higher risk profile of the RT group (larger thrombus, more rescue PCIs, longer symptom duration) . In the rescue PCI subgroup, RT demonstrated increased TIMI-3 flow postprocedure and lower mortality compared to pPCI. Hence, adjunctive RT might be beneficial in high risk subgroups of STEMI patients e.g. those with large thrombus . In accord with this, RT compared to PCI alone in patients with large thrombus resulted in higher TIMI flow, MBG, and absence of thrombus, which was associated with a higher 2-year cumulative survival and MACE-free survival . Another study showed that STEMI patients with moderate-to-large thrombus treated with RT compared to pPCI alone had better TIMI flow post-PCI with less no-reflow, better MBG, and a trend towards lower 30-day and 1-year MACE . The recent JetSTENT trial in 501 STEMI patients with large thrombus burden (TB), showed better STR and lower MACE at 6 months and 1 year with RT versus direct stenting alone . The difference in clinical outcome was driven by death and target vessel revascularization. This trial was very well designed and conducted, with inclusion only of patients with angiographic evidence of moderate-large thrombus, or an occluded artery following coronary wiring. Activation of the RT catheter was done proximal to the thrombus and a single pass was performed to decrease the risk of embolization. In contrast to the TAPAS and AiMI trials, in the JETSTENT trial, routine direct stenting without pre- or postdilation was applied in both arms (thrombectomy vs. stenting), along with routine use of abciximab in both arms. Thus the results of the JETSTENT trial have revived the concept of RT especially for AMI patients with large TB. Non-randomized registry data further reinforced the concept of benefit with RT in STEMI patients with large TB, as it was associated with reduced distal embolization, thereby improving MBG and TIMI flow, which led to a trend toward lower 1-year mortality . These promising new data regarding RT have not been incorporated in the guidelines for PCI and/or STEMI [6-8]. Besides needing an increased procedural time, RT is considered relatively safe, however care must exerted in case of severe tortuosity, especially in small vessels (< 2.0 mm), to avoid disruption of the artery . Hemodynamically significant AV block may complicate the procedure, especially when the RCA (or dominant left circumflex) is involved, thus some operators recommend placement of a temporary pacemaker, although temporary pacemakers were not used in the JetSTENT Trial . Specific technical precautions include avoiding balloon predilatation, activating the device at least 1 cm proximal to the thrombus before advancing beyond the lesion, advancement speed of 1-3 mm per second, and keeping the device activated during multiple passages until all visible thrombus disappears .
Most studies and meta-analyses -until recently- tend to concur that the benefit of thrombectomy in STEMI appears to be dependent on the type of technique used, with no clinical benefit for routine MT. However, no direct comparison of the two techniques exists.
A meta-analysis of 27 trials using showed benefit of AT and possible harm of MT during pPCI for STEMI . This result seems to have been driven by the AiMI study. Similarly, a meta-analysis of 11 trials using a patient level analysis showed that only STEMI patients treated with AT -and not MT- experienced a mortality and MACE reduction, especially if glycoprotein IIb/IIIa inhibitors were used . This meta-analysis included only two small studies of MT, using AngioJet , and X-Sizer . Another two studies registered as MT in this meta-analysis, used the TVAC, (Nipro's TransVascular Aspiration Catheter, Osaka, Japan), which is a single lumen aspiration catheter with a dedicated vacuum pump , and the Rescue catheter (Boston Scientific), which is an aspiration catheter . On the contrary, the latest Bayesian meta-analysis of 16 AT trials and 5 MT trials (4299 patients), that reported separately the aspiration results, showed that thrombectomy in general is associated only with improved surrogate procedural end-points, with equipoise results between AT and MT . The JetSTENT trial that followed the above meta-analyses, revived interest in RT . It may be that these two techniques (AT vs. MT) have differential benefits relative to the angiographic situation applied. For example, AT is not always successful, especially in patients with large thrombus, and may also promote by itself distal embolization and no-reflow , whereas RT is very effective in removing large thrombus [21-24, 26]. Therefore, large studies comparing the two techniques, possibly under different angiographic scenarios are needed. Until then, AT remains the recommended technique for adjunctive thrombectomy in STEMI [6-8].
Most thrombectomy studies have compared thrombectomy with PCI in an all-comers basis. A study with negative results (larger infarct size), using the Rescue catheter as routine therapy in 215 patients with STEMI, concluded that thrombectomy should not be used in unselected pPCI patients . This, combined with recent evidence on better results of RT in patients with large thrombus burden (TB) [21-24], and cost considerations, raise the issue of defining certain subgroups of patients which may benefit the most from thrombectomy. As large TB (visible thrombus size ≥ 2 vessel diameter), during pPCI, is associated with adverse procedural and clinical outcomes compared to small TB [30, 31], it has been proposed that patients with higher TB grade might benefit the most from thrombectomy. This concept, has been tested only in recent studies using RT [21-24].
The largest study enrolling only patients with large TB is the JetSTENT trial. The positive results of the latter contrary to AiMI, were partly attributed to the selected population of high risk patients enrolled. On the other hand, there is lack of data regarding possible differential benefits of AT relative to the TB due to universal application and insufficient numbers of patients to evaluate subgroups in AT studies. Hence, application of AT only in STEMIpatients with large TB, is not officially recommended [6-8]. However, experts are proposing direct stenting for low-grade thrombus, and application of any thrombectomy selectively only in patients with visible thrombus . A further segregation according to TB gradeproposes, AT for moderate thrombus and RT for high-grade thrombus. For patients with total occlusion of the vessel, (60% of STEMI patients) , direct use of a thrombectomy device, (Figs. 1, 3), or alternatively establishing reperfusion using a wire, or by Dottering, or by dilatation with a small balloon, is recommended, as it may help to reclassify up to 97% of patients [26, 31], (Fig. 2). (Fig. 5), shows a proposed algorithm for use of thrombectomy devices in STEMI.
Angioplasty of Saphenous Vein Grafts (SVGs), especially when there is total occlusion, has poor long-term results compared to native vessels PCI [6, 32-34]. Suboptimal results have been attributed to the larger TB and the large/friable plaque mass of old SVGs, leading to distal embolization/no-reflow [33, 35]. In our experience, visible angiographic thrombus is present in approximately 20% of ACS patients with culprit old SVG lesions . However, using optical coherence tomography, thrombus was detected in 46% of such lesions, being significantly more frequent in patients with STEMI . (Fig. 4). A number of treatment options are available for SVG-PCI in the setting of ACS (including acute occlusion), such as covered stents, distal filter protection (DFP), and thrombectomy. Although DFP is a Class-I indication for all SVG-PCI to prevent distal embolization , DFP devices may not be easily and/or safely used in occluded SVGs, or in SVGs perfusing more than one native vessels. Additionally, large TB and friable tissue may cause filter overloading . Although thrombectomy might be an alternative, there are no large studies examining the potential benefit of the latter in SVG-PCI. Despite this, in some centers thrombectomy has been reported to be the main adjunctive technique involved for contemporary PCI of old acutely occluded SVGs, with good results .
Thrombus aspiration is relatively easy in SVGs due to their large caliper, and has been successfully performed even with the guiding catheter . As DFP constitutes the standard of care for SVG-PCI , when dealing with thrombotic SVGs, combination with thrombectomy seems attractive. This concept is not new, as one distal protection device involving an occlusive balloon (PercuSurge GuardWire, Medtronic AVE, Minneapolis, Minnesota), allows for AT . Its use during stenting in diseased SVGs reduces periprocedural complications . However there is no agreement as to whether this system may induce balloon injury on the vein graft wall when visible atherosclerotic disease is present.[40, 41] As there is no available device combining AT with nonocclusive DFP, sequential use of two such devices has been proposed. This strategy has been tested in patients at high risk for distal embolization in both native coronaries and SVGs, and found to be feasible and successful [35, 38]. However, in a series of 25 consecutive patients with SVG lesions treated with AT before stenting with the combined use of the FilterWire EX/EZ (Boston Scientific Corp., Natick, Massachusetts), the incidence of no reflow was not reduced, compared to use of DFP alone . Hence, the possible benefits of such a strategy should be prospectively tested taking into account the increased complexity of the procedure.
A high procedural success (91%) has been reported with RT in 72 patients with ACS (unstable angina, or MI) and angiographic thrombus, including 33 (46%) SVG interventions . A multicentre study using X-SIZER, in 797 patients with 839 diseased SVGs or thrombus-containing native coronaries, found that this strategy did not reduce peri-procedural MI or MACES at 30 days and 1 year compared to PCI alone, although the rate of large MI was reduced . In contrast, both balloon occlusion/aspiration and DFP devices reduced the incidence of small and large MI. Finally, cases of successful combination of RT with the PercuSurge distal balloon occlusion device have been reported . In general, both AT and MT and their combination with DFP are feasible, and may be useful in the management of highly thrombotic infarct-related arteries/SVGs, however proper testing of this hypothesis is needed .
Aspiration thrombectomy, as an adjunct to PCI in thrombotic native lesions (mainly during pPCI), is effective and safe, and could possibly benefit the most patients with a large TB. New evidence also suggests that RT might be beneficial for such patients. Sequential application of manual/mechanical thrombectomy and DFP might be a reasonable approach for thrombotic SVG lesions, however robust evidence is still lacking.
The authors confirm that this article content has no conflicts of interest.
|1.||Keeley EC,Boura JA,Grines CL. Primary angioplasty versus intravenous thrombolytic therapy for acute myocardial infarction: A quantitative review of 23 randomised trialsLancetYear: 2003361132012517460|
|2.||Hamm CW,Bassand JP,Agewall S,et al. ESC guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation: The task force for the management of acute coronary syndromes (ACS) in patients presenting without persistent ST-segment elevation of the european society of cardiology (ESC)Eur Heart JYear: 2011322999305421873419|
|3.||Henriques JP,Zijlstra F,Ottervanger JP,et al. Incidence and clinical significance of distal embolization during primary angioplasty for acute myocardial infarctionEur Heart JYear: 2002231112111712090749|
|4.||Klein LW,Kern MJ,Berger P,et al. Society of cardiac angiography and interventions: Suggested management of the no-reflow phenomenon in the cardiac catheterization laboratoryCatheter Cardiovasc IntervYear: 20036019420114517924|
|5.||Szerlip M,Grines CL. The current role of angiojet rheolytic thrombectomy in acute myocardial infarctionJ Invasive Cardiol2221B22B|
|6.||Wijns W,Kolh P,Danchin N,et al. Guidelines on myocardial revascularizationEur Heart J312501255520802248|
|7.||Levine GN,Bates ER,Blankenship JC,et al. 2011 ACCF/AHA/ SCAI guideline for percutaneous coronary intervention.A report of the american college of cardiology foundation/american heart association task force on practice guidelines and the society for cardiovascular angiography and interventions J Am Coll Cardiol58e4412222070834|
|8.||Kushner FG,Hand M,Smith SC Jr,et al. 2009 focused updates: ACC/AHA guidelines for the management of patients with ST-elevation myocardial infarction (updating the 2004 guideline and 2007 focused update) and ACC/AHA/SCAI guidelines on percutaneous coronary intervention (updating the 2005 guideline and 2007 focused update): A report of the american college of cardiology foundation/american heart association task force on practice guidelinesCirculationYear: 20091202271230619923169|
|9.||Sardella G,Mancone M,Bucciarelli-Ducci C,et al. Thrombus aspiration during primary percutaneous coronary intervention improves myocardial reperfusion and reduces infarct size: The EXPIRA (thrombectomy with export catheter in infarct-related artery during primary percutaneous coronary intervention) prospective, randomized trialJ Am Coll CardiolYear: 20095330931519161878|
|10.||Svilaas T,Vlaar PJ,van der Horst IC,et al. Thrombus aspiration during primary percutaneous coronary interventionN Engl J MedYear: 200835855756718256391|
|11.||Vlaar PJ,Svilaas T,van der Horst IC,et al. Cardiac death and reinfarction after 1 year in the thrombus aspiration during percutaneous coronary intervention in acute myocardial infarction study (tapas): A 1-year follow-up studyLancetYear: 20083711915192018539223|
|12.||Brodie BR. Aspiration thrombectomy with primary pci for stemi: Review of the data and current guidelinesJ Invasive Cardiol222B5B20048389|
|13.||Bavry AA,Kumbhani DJ,Bhatt DL. Role of adjunctive thrombectomy and embolic protection devices in acute myocardial infarction: A comprehensive meta-analysis of randomized trialsEur Heart JYear: 2008292989300118812323|
|14.||De Luca G,Dudek D,Sardella G,Marino P,Chevalier B,Zijlstra F. Adjunctive manual thrombectomy improves myocardial perfusion and mortality in patients 15 undergoing primary percutaneous coronary intervention for ST-elevation myocardial in-farction: A meta-analysis of randomized trialsEur Heart JYear: 2008293002301018775918|
|15.||Burzotta F,De Vita M,Gu YL,et al. Clinical impact of thrombectomy in acute stelevation myocardial infarction: An individual patient-data pooled analysis of 11 trialsEur Heart JYear: 2009302193220319726437|
|16.||Mongeon FP,Belisle P,Joseph L,Eisenberg MJ,Rinfret S. Adjunctive thrombectomy for acute myocardial infarction: A bayesian meta-analysisCirc Cardiovasc Interv361620118149|
|17.||Ischinger T. Thrombectomy with the x-sizer catheter system in the coronary circulation: Initial results from a multi-center studyJ Invasive CardiolYear: 200113818811176013|
|18.||Antoniucci D,Valenti R,Migliorini A,et al. Comparison of rheolytic thrombectomy before direct infarct artery stenting versus direct stenting alone in patients undergoing percutaneous coronary intervention for acute myocardial infarctionAm J CardiolYear: 2004931033103515081450|
|19.||Silva JA,White CJ,Ramee SR,et al. Treatment of coronary stent thrombosis with rheolytic thrombectomy: Results from a multicenter experienceCatheter Cardiovasc IntervYear: 200358111712508190|
|20.||Ali A,Cox D,Dib N,et al. Rheolytic thrombectomy with percutaneous coronary intervention for infarct size reduction in acute myocardial infarction: 30-day results from a multicenter randomized studyJ Am Coll CardiolYear: 20064824425216843170|
|21.||Grines CL,Nelson TR,Safian RD,et al. A bayesian meta-analysis comparing angiojet thrombectomy to percutaneous coronary intervention alone in acute myocardial infarctionJ Interv CardiolYear: 200821459482 1619018943|
|22.||Sianos G,Papafaklis MI,Vaina S,et al. Rheolytic thrombectomy in patients with STelevation myocardial infarction and large thrombus burden: The Thoraxcenter experienceJ Invasive CardiolYear: 200618Suppl C3C7C|
|23.||Sharma SK,Tamburrino F,Mares AM,Kini AS. Improved outcome with angiojet thrombectomy during primary stenting in acute myocardial infarction patients with high-grade thrombusJ Invasive CardiolYear: 200618 Suppl CC81116883025|
|24.||Migliorini A,Stabile A,Rodriguez AE,et al. Comparison of angiojet rheolytic thrombectomy before direct infarct artery stenting with direct stenting alone in patients with acute myocardial infarction. The jetstent trialJ Am Coll Cardiol561298130620691553|
|25.||Sharma SK. Role of angiojet rheolytic thrombectomy catheter: Mount sinai hospital experienceJ Invasive Cardiol2215B20B20048393|
|26.||Brodie BR,Sianos G,Grines CL,Antoniucci D,Mehta S,Sharma SK. Panel summary and recommendations on the role of thrombectomy with primary pci for stemiJ Invasive Cardiol2234B35B|
|27.||Lefevre T,Garcia E,Reimers B,et al. X-sizer for thrombectomy in acute myocardial infarction improves st-segment resolution: Results of the x-sizer in ami for negligible embolization and optimal st resolution (X AMINE ST) trialJ Am Coll CardiolYear: 20054624625216022950|
|28.||Ikari Y,Sakurada M,Kozuma K,et al. Upfront thrombus aspiration in primary coronary intervention for patients with ST-segment elevation acute myocardial infarction: Report of the VAMPIRE (vacuum aspiration thrombus removal) trialJACC Cardiovasc IntervYear: 20081424431 17. 19463340|
|29.||Kaltoft A,Bottcher M,Nielsen SS,et al. Routine thrombectomy in percutaneous coronary intervention for acute ST-segment-elevation myocardial infarction: A randomized, controlled trialCirculationYear: 2006114404716801464|
|30.||Sianos G,Papafaklis MI,Daemen J,et al. Angiographic stent throm-bosis after routine use of drug-eluting stents in ST-segment elevation myocardial infarction: The importance of thrombus burdenJ Am Coll CardiolYear: 20075057358317692740|
|31.||Sianos G,Papafaklis MI,Serruys PW. Angiographic thrombus burden classification in patients with ST-segment elevation myocardial infarction treated with percutaneous coronary interventionJ Invasive Cardiol226B14B20048390|
|32.||Roffi M,Mukherjee D,Chew DP,et al. Lack of benefit from intravenous platelet glycoprotein IIb/IIIa receptor inhibition as adjunctive treatment for percutaneous interventions of aortocoronary bypass grafts: A pooled analysis of five randomized clinical trialsCirculationYear: 20021063063306712473552|
|33.||Abdel-Karim AR,Banerjee S,Brilakis ES. Percutaneous intervention of acutely occluded saphenous vein grafts: Contemporary techniques and outcomesJ Invasive CardiolYear: 20102225325720516502|
|34.||Xanthopoulou I,Davlouros P,Tsigkas G,et al. Long-term clinical outcome after percutaneous coronary intervention in grafts vs native vessels in patients with previous coronary artery bypass graftingCan J CardiolYear: 00002771672422019279|
|35.||Hamilos MI,Kochiadakis GE,Karalis I,Skalidis EI,Igoumenidis NE,Vardas PE. Combined use of aspiration catheter and distal embolisation protection device to facilitate angioplasty of a totally occluded saphenous vein graftHellenic J CardiolYear: 200748117121 1817489351|
|36.||Davlouros P,Damelou A,Karantalis V,et al. Evaluation of culprit saphenous vein graft lesions with optical coherence tomography in patients with acute coronary syndromesJACC Cardiovasc Interv468369321700255|
|37.||Moscucci M,Punamiya K,Ricciardi MJ. Guiding catheter thrombectomy during percutaneous coronary interventions for acute coronary syndromesCatheter Cardiovasc IntervYear: 20004919219610642772|
|38.||Burzotta F,Trani C,Romagnoli E,et al. Feasibility of sequential thrombus aspiration and filter distal protection in the management of very high thrombus burden lesionsJ Invasive CardiolYear: 20071931732317712197|
|39.||Baim DS,Wahr D,George B,et al. Randomized trial of a distal embolic protection device during percutaneous intervention of saphenous vein aorto-coronary bypass graftsCirculationYear: 20021051285129011901037|
|40.||Sharma N,Kalaria VG. Inadvertent dilation of a saphenous vein graft stenosis by the percusurge guardwire distal protection balloonCatheter Cardiovasc IntervYear: 20035934634912822155|
|41.||Agostoni P,Vermeersch P,Vydt T,et al. Acute and mid-term local vascular effects of compliant balloon inflation (guardwire system) on saphenous vein bypass grafts: An angiographic analysisInt J CardiolYear: 200712022723117175046|
|42.||Jim MH,Yiu KH,Ko RL,Ho HH,Siu CW,Chow WH. Manual aspiration prior to stenting does not reduce the incidence of filter no reflow in saphenous vein graft lesions protected by filterwire ex/ezAcute Card CareYear: 201012929520677906|
|43.||Singh M,Tiede DJ,Mathew V,et al. Rheolytic thrombectomy with angiojet in thrombus-containing lesionsCatheter Cardiovasc IntervYear: 20025617 1911979522|
|44.||Stone GW,Cox DA,Babb J,et al. Prospective, randomized evaluation of thrombectomy prior to percutaneous intervention in diseased saphenous vein grafts and thrombus-containing coronary arteriesJ Am Coll CardiolYear: 2003422007201314662267|
|45.||Gaitonde RS,Sharma N,von der Lohe E,Kalaria VG. Combined distal embolization protection and rheolytic thrombectomy to facilitate percutaneous revascularization of totally occluded saphenous vein graftsCatheter Cardiovasc IntervYear: 20036021221714517927|
Keywords: Keywords Thrombectomy, percutaneous coronary intervention, vein grafts..
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