Document Detail

Thrombotic thrombocytopenic purpura.
MedLine Citation:
PMID:  1171419     Owner:  NLM     Status:  MEDLINE    
The patient reported here is the twentieth reported case of thrombotic thrombocytopenia purpura (TTP) occurring in pregnancy, the third survivor, and the first to be delivered by cesarean section. Diagnosis of TTP is usually made on the basis of the pentad of anemia, thrombocytopenia, renal disease, neurologic abnormalities, and fever. A peripheral smear showing microangiopathic hemolysis can be confirmatory and may even be regarded as a definitive test in questionable cases of thrombocytopenia. Although splenectomy, steroids, heparin, and early delivery have been recommended, splenectomy is the only treatment showing a statistically significant improvement in survival rate; 60% of infants born at or beyond 33 weeks' gestation have survived.
C Barrett; J R Marshall
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Obstetrics and gynecology     Volume:  46     ISSN:  0029-7844     ISO Abbreviation:  Obstet Gynecol     Publication Date:  1975 Aug 
Date Detail:
Created Date:  1975-11-06     Completed Date:  1975-11-06     Revised Date:  2009-10-26    
Medline Journal Info:
Nlm Unique ID:  0401101     Medline TA:  Obstet Gynecol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  231-4     Citation Subset:  AIM; IM    
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MeSH Terms
Blood Cell Count
Cesarean Section
Diagnosis, Differential
Infant, Newborn
Obstetric Labor Complications
Pregnancy Complications, Hematologic* / diagnosis,  therapy
Purpura, Thrombotic Thrombocytopenic* / diagnosis,  therapy
Spleen / pathology

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