Document Detail

Thrombotic thrombocytopenic purpura with complete molar pregnancy: a case report.
MedLine Citation:
PMID:  21542537     Owner:  NLM     Status:  In-Process    
BACKGROUND: Thrombotic thrombocytopenic purpura (TTP) is extremely rare. This disease and its prompt diagnosis are important because TTP in pregnancy carries a 90% mortality rate.
CASE: A 21-year-old woman underwent suction dilation and curettage for molar pregnancy. Postoperatively the patient developed severe hypertension, microangiopathic anemia, thrombocytopenia and chest pain associated with ischemic cardiac changes. Despite blood and plasma transfusions and steroid therapy, the patient continued to have worsening hemolysis and thrombocytopenia. TTP was diagnosed, and plasmapheresis led to a rapid recovery.
CONCLUSION: TTP can occur with molar pregnancy. Making this diagnosis in a timely manner is crucial to ensure that potentially life-saving plasmapheresis is initiated in a timely manner. To our knowledge, this is the first reported case of thrombotic thrombocytopenic purpura with molar pregnancy.
Hongmei Meng; Nirmala S Kumar; Jyothi Nannapaneni; Steven R Inglis
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Journal of reproductive medicine     Volume:  56     ISSN:  0024-7758     ISO Abbreviation:  J Reprod Med     Publication Date:    2011 Mar-Apr
Date Detail:
Created Date:  2011-05-05     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0173343     Medline TA:  J Reprod Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  169-71     Citation Subset:  IM    
Department of Obstetrics and Gynecology, Jamaica Hospital Medical Center, Jamaica, New York 11418, USA.
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