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Thrombotic thrombocytopenic purpura mimicking an acute meningoencephalitis.
MedLine Citation:
PMID:  21485766     Owner:  NLM     Status:  In-Process    
Abstract/OtherAbstract:
Thrombotic thrombocytopenic purpura is a rare, threatening disease characterized by thrombocytopenia, microangiopathic haemolytic anaemia and organ dysfunction, e.g., neurological impairment and renal insufficiency. We describe a patient with neurological impairment mimicking a meningoencephalitis in whom a thorough clinical evaluation along with appropriate laboratory tests led us to identify an underlying thrombotic thrombocytopenic purpura. The successful outcome of this patient was based on plasma exchange and immunosuppressive treatment. Thrombotic thrombocytopenic purpura should be considered in the differential diagnosis of patients presenting with any neurological abnormalities, anaemia and unexplained thrombocytopenia.
Authors:
F Tovoli; R De Giorgio; A Fabbri; M Serra; G Caio; V Grasso; C Felicani; G Barbara; U Volta
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Acta clinica Belgica     Volume:  66     ISSN:  0001-5512     ISO Abbreviation:  Acta Clin Belg     Publication Date:    2011 Jan-Feb
Date Detail:
Created Date:  2011-04-13     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0370306     Medline TA:  Acta Clin Belg     Country:  Belgium    
Other Details:
Languages:  eng     Pagination:  55-6     Citation Subset:  IM    
Affiliation:
Dipartimento di Medicina Clinica, Università di Bologna, Bologna, Italy.
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