Document Detail

Thrombotic thrombocytopenic purpura in a patient with very early pregnancy: clinical presentation and autopsy findings.
MedLine Citation:
PMID:  18832919     Owner:  NLM     Status:  MEDLINE    
Thrombotic thrombocytopenic purpura is a thrombotic microangiopathy leading to microvascular occlusion resulting in ischemic dysfunction of various organs. Pregnancy has been thought to precipitate it during second and third trimester, but its reports in first trimester are extremely rare. We report the clinical protocol of a young lady with 5-week period of gestation, who presented with fever, seizures and altered sensorium, and succumbed to her illness during an episode of seizure. Complete autopsy findings are also presented in detail.
Aman Sharma; Bishan Radotra; Ajay Wanchu; Pankaj Malhotra; Surjit Singh; Subhash Varma
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis     Volume:  19     ISSN:  0957-5235     ISO Abbreviation:  Blood Coagul. Fibrinolysis     Publication Date:  2008 Oct 
Date Detail:
Created Date:  2008-10-03     Completed Date:  2009-03-19     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9102551     Medline TA:  Blood Coagul Fibrinolysis     Country:  England    
Other Details:
Languages:  eng     Pagination:  727-30     Citation Subset:  IM    
Department of Internal Medicine, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
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MeSH Terms
Fatal Outcome
Microscopy, Electron
Pregnancy Complications, Hematologic / pathology*
Purpura, Thrombotic Thrombocytopenic / pathology*

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