| Thrombotic occlusion of the common carotid artery (CCA) in acute ischemic stroke treated with intravenous tissue plasminogen activator (TPA). | |
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MedLine Citation:
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PMID: 17250737 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Although common carotid artery (CCA) occlusions are rare, acute clinical presentations vary from mild to devastating strokes primarily due to tandem occlusions in the intracranial arteries. Three patients with acute CCA occlusions were treated with systemic tissue plasminogen activator (TPA). Blood pressures were kept at the upper limits allowed with TPA therapy with fluid balance and the 'head-down' position. Recanalization occurred in intracranial vessels only. Marked early neurological improvement occurred in two of three patients. CCA occlusions should not be considered contra-indication to systemic thrombolysis. |
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Authors:
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V K Sharma; G Tsivgoulis; A Y Lao; M Flaster; J L Frey; M D Malkoff; A V Alexandrov |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: European journal of neurology : the official journal of the European Federation of Neurological Societies Volume: 14 ISSN: 1468-1331 ISO Abbreviation: Eur. J. Neurol. Publication Date: 2007 Feb |
Date Detail:
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Created Date: 2007-01-25 Completed Date: 2007-02-23 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 9506311 Medline TA: Eur J Neurol Country: England |
Other Details:
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Languages: eng Pagination: 237-40 Citation Subset: IM |
Affiliation:
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Department of Neurology, Barrow Neurological Institute, Phoenix, AZ 85013, USA. drvijay@singnet.com.sg |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Acute Disease Aged Aged, 80 and over Angiography, Digital Subtraction Brain Ischemia / etiology* Carotid Artery Thrombosis / complications*, diagnosis, drug therapy* Carotid Artery, Common* Cerebral Angiography Female Fibrinolytic Agents / therapeutic use* Humans Male Nervous System / drug effects, physiopathology Recovery of Function Stroke / etiology*, physiopathology Tissue Plasminogen Activator / therapeutic use* Tomography, X-Ray Computed Treatment Outcome Ultrasonography, Doppler, Duplex |
| Chemical | |
Reg. No./Substance:
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0/Fibrinolytic Agents; EC 3.4.21.68/Tissue Plasminogen Activator |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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