Document Detail


Thrombosis and restenosis after stenting in failed angioplasty: comparison with elective stenting.
MedLine Citation:
PMID:  8017264     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The results of Palmaz-Schatz stent implantation in failed angioplasty in 60 consecutive patients were compared with those of elective stent implantation in 100 consecutive patients. Stent implantation was successful in all of the failed group and in 99% of the elective. Stent thrombosis occurred in 16.7% of the failed group and 2% of the elective (p = 0.001). In the failed angioplasty group, stent thrombosis was associated with a greater frequency of preprocedure complex morphology (40% vs 12% in the nonthrombosis group, p = 0.05), persistent uncovered dissection after stenting (60% vs 14%, p = 0.004), and greater residual stenosis (39.9% +/- 25.3% vs 24.9% +/- 13.08%, p = 0.008) after stenting. Vessel patency was reestablished by angioplasty in 5 of 10 with stent thrombosis. Of these 5 patients, however, 2 suffered repeat stent thrombosis; 1 died suddenly four months later; and restenosis occurred in the remaining 2. Follow-up angiography was performed in 98% of the elective group at 6.3 +/- 2.6 months and 96% of the failed angioplasty group at 6.4 +/- 2.1 months. Restenosis (> or = 50% stenosis) occurred in 32% of the elective group and 50% of the failed angioplasty group (p = 0.041). Multiple logistic regression analysis identified multiple stent implantation (F = 6.75, p = 0.01) and triple-vessel disease (F = 3.46, p = 0.06) as independent positive predictors of restenosis. In conclusion, stent implantation in cases of failed angioplasty could be performed with a success similar to that of elective stent implantation but was associated with a greater frequency of stent thrombosis and restenosis.
Authors:
J B Foley; R I Brown; I M Penn
Related Documents :
10377304 - Use of self expanding stents in stenotic aortopulmonary shunts in adults with complex c...
10426874 - Current role of stenting in acute myocardial infarction.
11066104 - Primary stenting in nonselected patients with acute myocardial infarction: the multilin...
11515014 - Local delivery of paclitaxel using the double-balloon perfusion catheter before stentin...
8565174 - Angiotensin-converting enzyme inhibition preserves endothelium-dependent coronary micro...
7771164 - Torsades de pointes and aborted sudden death after implantation of a cardioverter defib...
Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  American heart journal     Volume:  128     ISSN:  0002-8703     ISO Abbreviation:  Am. Heart J.     Publication Date:  1994 Jul 
Date Detail:
Created Date:  1994-07-28     Completed Date:  1994-07-28     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0370465     Medline TA:  Am Heart J     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  12-20     Citation Subset:  AIM; IM    
Affiliation:
Victoria Hospital, University of Western Ontario, London, Canada.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Age Factors
Angina, Unstable / physiopathology
Angioplasty, Transluminal, Percutaneous Coronary / adverse effects*,  methods
Cause of Death
Constriction, Pathologic / pathology
Coronary Disease / pathology,  therapy*
Coronary Vessels / injuries,  pathology
Equipment Design
Female
Fibrinolytic Agents / therapeutic use
Follow-Up Studies
Hemorrhage / etiology
Humans
Male
Middle Aged
Myocardial Infarction / etiology
Myocardial Ischemia / physiopathology
Recurrence
Stents / adverse effects*
Thrombosis / etiology*
Treatment Failure
Vascular Patency
Chemical
Reg. No./Substance:
0/Fibrinolytic Agents

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Effect of altered contractility on the linearity of regional left ventricular end-systolic relations...
Next Document:  Effects of low-dose flosequinan on left ventricular systolic and diastolic chamber performance.