Document Detail

Thrombosis of non-giant unruptured aneurysms causing ischemic stroke.
MedLine Citation:
PMID:  20433779     Owner:  NLM     Status:  MEDLINE    
OBJECTIVES: To describe a series of patients with stroke secondary to thrombosis in unruptured non-giant aneurysms and to classify them.
METHODS: Patients with saccular non-giant aneurysm thrombosis presenting with ischemic events were identified. The clinical and imaging attributes were then used to build a novel classification scheme for aneurysm-related stroke.
RESULTS: Six patients were included representing 0.15% of all strokes. The proposed mechanisms for stroke were classified as dislodgement of aneurysm thrombi to distal vessels, extension of aneurysm clot into the parent vessel and parent vessel occlusion due to extrinsic compression by the thrombosed aneurysm. Stroke severity was minor and outcome was excellent in all patients.
CONCLUSIONS: Strokes caused by unruptured aneurysms are rare and can be caused by several mechanisms. Clinicians should be aware of this rare form of stroke as it may represent a contraindication to systemic thrombolysis due to increased risk of aneurysm recanalization and rupture.
José E Cohen; John M Gomori; Ronen R Leker
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2010-04-30
Journal Detail:
Title:  Neurological research     Volume:  32     ISSN:  1743-1328     ISO Abbreviation:  Neurol. Res.     Publication Date:  2010 Nov 
Date Detail:
Created Date:  2010-10-04     Completed Date:  2011-01-24     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7905298     Medline TA:  Neurol Res     Country:  England    
Other Details:
Languages:  eng     Pagination:  971-4     Citation Subset:  IM    
Department of Neurosurgery, Hadassah Hebrew University Hospital, Jerusalem, Israel.
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MeSH Terms
Intracranial Aneurysm / complications*
Magnetic Resonance Angiography / methods
Magnetic Resonance Imaging / methods
Middle Aged
Prospective Studies
Stroke / diagnosis,  etiology*
Thrombosis / complications*,  etiology*
Tomography, X-Ray Computed / methods

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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