Document Detail

Thrombosis in pregnancy: maternal and fetal issues.
MedLine Citation:
PMID:  10217099     Owner:  NLM     Status:  MEDLINE    
Pulmonary thromboembolism is the main cause of maternal death in the UK and current trends show an increase. Deep-vein thrombosis underlies this disorder. Important issues include pathophysiology, diagnosis, and management of thrombosis in pregnancy, especially the use of anticoagulants. Congenital and acquired thrombophilias contribute to the pathophysiological processes that underlie miscarriage, intrauterine growth restriction, and pre-eclampsia, and raises new possibilities for intervention. The high prevalence of thrombophilic defects in the population, the association of defects with maternal and fetal disorders, and special considerations for management make it essential for obstetricians to understand this area.
I A Greer
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Lancet     Volume:  353     ISSN:  0140-6736     ISO Abbreviation:  Lancet     Publication Date:  1999 Apr 
Date Detail:
Created Date:  1999-05-13     Completed Date:  1999-05-13     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  2985213R     Medline TA:  Lancet     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  1258-65     Citation Subset:  AIM; IM    
Department of Obstetrics and Gynaecology, University of Glasgow, Glasgow Royal Infirmary, UK.
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MeSH Terms
Anticoagulants / therapeutic use
Fetal Death / etiology
Pregnancy Complications, Cardiovascular*
Pulmonary Embolism / etiology*,  prevention & control
Thrombophilia / classification,  complications,  congenital*
Venous Thrombosis / complications*,  drug therapy,  epidemiology,  etiology
Reg. No./Substance:
Comment In:
Lancet. 1999 Jul 10;354(9173):162-3   [PMID:  10408516 ]

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