Document Detail

Thrombosis and embolism in pediatric cardiomyopathy.
MedLine Citation:
PMID:  23429248     Owner:  NLM     Status:  Publisher    
The management of cardiomyopathy in pediatric patients is complicated by the risk of cardiac-associated embolism. This review examines the incidence, risk factors, and treatment of embolism in dilated cardiomyopathy (DCM), restrictive cardiomyopathy (RCM), and noncompaction of the left ventricular myocardium (NLVM) in children. The reported incidence of embolism for DCM ranges from 1 to 16%. Left ventricular ejection fraction below 25% or fractional shortening below 15% are major risk factors for intracardiac thrombus formation in this group. The risk of embolism for RCM ranges from 12 to 33%. Atrial dilation is considered the major risk factor. The reported incidence of embolism for NLVM ranges from 0 to 38%, with most studies indicating an absence of detectable thrombus or embolus. Severe systolic dysfunction exacerbates the risk of embolism in this group. On the basis of these risk factors, we propose an algorithm for the management of embolism in these groups of patients.
Kai Chen; Suzan Williams; Anthony K C Chan; Tapas K Mondal
Related Documents :
15752228 - Calcification and cardiovascular problems in renal failure.
24460608 - Hypericin as a marker for determination of myocardial viability in a rat model of myoca...
23608108 - Synthesis and characterization of (123)i-cmice-013: a potential spect myocardial perfus...
24089028 - Hypoxia-inducible factor-1α polymorphisms link to coronary artery collateral developme...
19653918 - Protective effects of hydroalcoholic extract from rhizomes of cynodon dactylon (l.) per...
20691318 - Early repolarization, left ventricular diastolic function, and left atrial size in prof...
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-2-20
Journal Detail:
Title:  Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis     Volume:  -     ISSN:  1473-5733     ISO Abbreviation:  Blood Coagul. Fibrinolysis     Publication Date:  2013 Feb 
Date Detail:
Created Date:  2013-2-22     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9102551     Medline TA:  Blood Coagul Fibrinolysis     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
aMcMaster University, Hamilton bHospital for Sick Children, University of Toronto, Toronto cMcMaster Children's Hospital, McMaster University, Hamilton, Ontario, Canada.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Potent DNA damage by polyhalogenated quinones and H(2)O(2) via a metal-independent and Intercalation...
Next Document:  Life, limb or off-label recombinant VIIa use in the setting of limited blood assets: a case study.