Document Detail

Thromboprophylaxis with low molecular weight heparin after major orthopaedic surgery is cost effective.
MedLine Citation:
PMID:  9042559     Owner:  NLM     Status:  MEDLINE    
The objective of this analysis was to evaluate the socioeconomic consequences of routine administration of low molecular weight heparin (LMWH) as thromboprophylaxis in patients undergoing total hip arthroplasty, on the basis of data from a number of clinical studies. Despite the higher direct costs associated with LMWH, this regimen was more cost effective per thromboembolic complication prevented than no prophylaxis, dextran 70, or low dose unfractionated heparin. A sensitivity analysis was performed to address the outcome when the main factors in the economic analysis were changed; this had no significant effect on the conclusions of the study.
L C Borris; M R Lassen
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Drugs     Volume:  52 Suppl 7     ISSN:  0012-6667     ISO Abbreviation:  Drugs     Publication Date:  1996  
Date Detail:
Created Date:  1997-04-30     Completed Date:  1997-04-30     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7600076     Medline TA:  Drugs     Country:  NEW ZEALAND    
Other Details:
Languages:  eng     Pagination:  42-6     Citation Subset:  IM    
Venous Thrombosis Group, Aalborg Hospital, Denmark.
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MeSH Terms
Anticoagulants / economics*,  therapeutic use
Cost-Benefit Analysis
Heparin, Low-Molecular-Weight / economics*,  therapeutic use
Hip Prosthesis / adverse effects,  economics*
Postoperative Complications / economics*,  prevention & control
Thromboembolism / economics*,  prevention & control
Reg. No./Substance:
0/Anticoagulants; 0/Heparin, Low-Molecular-Weight

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