| Thrombomodulin Ala455Val dimorphism is not associated with pre-eclampsia in Australian and New Zealand women. | |
| | |
MedLine Citation:
|
PMID: 12297717 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Thrombomodulin plays an important role in thromboresistance. A common mutation of the gene at amino acid 455 producing valine instead of alanine has been implicated as being a risk factor in myocardial infarction and chronic heart disease. However, its link with pre-eclampsia remains controversial. This report explores the Ala455Val point mutation in 280 women as a predictor of pre-eclampsia with the conclusion that in this regard, the dimorphism is essentially neutral. |
| | |
Authors:
|
Anthony J Borg; John R Higgins; Shaun P Brennecke; Eric K Moses |
Related Documents
:
|
21627557 - Serum anti-müllerian hormone, inhibin b, and total inhibin levels in women with hypoth... 21950567 - Tgf-β1 content in atherosclerotic plaques, tgf-β1 serum concentrations and incident c... 21882017 - Serum anti-müllerian hormone and antral follicle count as predictive markers of ohss i... 22032897 - Dydrogesterone supplementation in women with threatened preterm delivery--the impact on... 17058327 - Mortality in schizophrenia. 9830187 - Endometrial sampling in general practice. |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
|
Title: Gynecologic and obstetric investigation Volume: 54 ISSN: 0378-7346 ISO Abbreviation: Gynecol. Obstet. Invest. Publication Date: 2002 |
Date Detail:
|
Created Date: 2002-09-25 Completed Date: 2002-12-17 Revised Date: 2006-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 7900587 Medline TA: Gynecol Obstet Invest Country: Switzerland |
Other Details:
|
Languages: eng Pagination: 43-5 Citation Subset: IM |
Copyright Information:
|
Copyright 2002 S. Karger AG, Basel |
Affiliation:
|
Department of Perinatal Medicine, The Royal Women's Hospital, Carlton, Vic., Australia. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Alleles Australia Base Sequence Cohort Studies DNA / chemistry, genetics Female Genetic Predisposition to Disease Humans Molecular Sequence Data Mutation / genetics New Zealand Polymerase Chain Reaction Polymorphism, Genetic / genetics* Pre-Eclampsia / genetics* Pregnancy Thrombomodulin / chemistry, genetics* |
| Chemical | |
Reg. No./Substance:
|
0/Thrombomodulin; 9007-49-2/DNA |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Anticipation of uterine bleeding in placenta previa based on vaginal sonographic evaluation.
Next Document: Screening for prolactin isoforms in the follicular fluid of patients undergoing in vitro fertilizati...