Document Detail

Thrombolytic therapy for a thrombosed Bjork-Shiley tricuspid valve prosthesis.
MedLine Citation:
PMID:  7094448     Owner:  NLM     Status:  MEDLINE    
A 67-year-old mand in whom mitral and tricuspid Bjork-Shiley tilting disc prostheses had been implanted 68 months previously presented with thrombotic obstruction of his tricuspid prosthesis. Initial cardiac catheterization demonstrated a significant transprosthetic tricuspid diastolic gradient (9.5 mmHg) with a calculated prosthetic valve orifice area (0.62 cm2) indicating a critical degree of stenosis. The resting cardiac index was markedly reduced (1.5 l/m2/min). Following an intravenous infusion of streptokinase for 66 hours, repeat cardiac catheterization revealed a 50% reduction in transprosthetic diastolic gradient across the tricuspid valve (4.7 mmHg), a greater than fourfold increase in prosthetic valve orifice area (2.87 cm2) with a normal resting cardiac index (3.1 l/m2/min).
K J Hellestrand; J J Morgan; V P Chang
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Clinical cardiology     Volume:  5     ISSN:  0160-9289     ISO Abbreviation:  Clin Cardiol     Publication Date:  1982 May 
Date Detail:
Created Date:  1982-09-24     Completed Date:  1982-09-24     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7903272     Medline TA:  Clin Cardiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  347-50     Citation Subset:  IM    
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MeSH Terms
Heart Catheterization
Heart Valve Prosthesis*
Infusions, Parenteral
Streptokinase / administration & dosage*
Thrombosis / drug therapy*
Tricuspid Valve*
Reg. No./Substance:
EC 3.4.-/Streptokinase

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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